Bacteriological profile in UTI Cases with special reference to Amikacin sensitivity in a tertiary Care centre in Western UP
Journal Title: IP International Journal of Medical Microbiology and Tropical Diseases - Year 2018, Vol 4, Issue 4
Abstract
Introduction UTI is the most common bacterial infection worldwide with adult women being 30 times more likely to suffer from it than men due to short urethra and proximity of uretheral opening with anal canal Escherichia coli is the most common organism responsible for UTI and there has been an increase in incidence of community acquired UTI caused by ESBL producing E coli This study was planned to see the sensitivity of amikacin in urinary isolates so it can be considered as a treatment option in ESBL producing organisms reserving highend drugs like carbapenemsMaterials and Methods The retrospective study was carried out between January 2017 to August 2017 with 1025 patients of suspected UTI being screened for growth of bacteria in their urine samples and their sensitivity to antibiotics Both males and females were included in the study ages ranging from 0 year to 80 yrs Urine samples were inoculated on Blood agar and MacConkey agar All positive cultures were tested for antibiotic susceptibility testing by Kirby bauer disc diffusion techniqueResults Out of total 1025 samples growth was detected in 171 167 samples Out of these 121 708 were females and 50 292 were males Maximum number of males are seen in age group 2130 yrs ie 13 26 followed by 41 to 50 yrs ie 12 24 Also maximum number of females are seen in age group 2130 yrs ie 41 339 followed by 21 174 patients in age group 4150yrs Most common microbial agent isolated was Ecoli 97171 followed by Klebsiella spp25171 The important finding of the study was the sensitivity pattern of amikacin in this area which was found to be sensitive in 61 of the isolates which is quite significant as we can use amikacin rather than high end antibiotics like carbapenems in sensitive cases in UTI and prevent emergence of resistance against themConclusion Our finding ie Amikacin being highly sensitive to urinary pathogens reflects upon the facts that in sensitive cases Amikacin can be used for ESBL producing uropathogens instead of costly high end antibiotics like CarbapenamsKeywords UTI ESBL producing E coli Amikacin
Authors and Affiliations
Ritu Agarwal, Gunjan Pandey
Keywords
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- EP ID EP485880
- DOI 10.18231/2581-4761.2018.0047
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