Bacteriological Study of Early Onset and Late Onset Neonatal Septicaemia in a Tertiary Care Hospital in South India
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 7
Abstract
Introduction: Neonatal septicaemia is a clinical syndrome characterised by signs and symptoms of infection with or without accompanying bacteraemia in the first month of life. It is classified into early onset sepsis within 72 hour of life and late onset sepsis after 72 hour. The varying microbiological pattern of septicemia and their high antibiotic resistance needs to be studied. Material and Methods: This retrospective observational study was conducted for a period of one year. The bacterial isolates and their antibiogram from blood samples of clinically suspected neonatal septicaemic cases were studied from the records of Microbiology Laboratory. Results:Among 350 blood samples collected from clinically suspected cases of neonatal septicaemia,50(14.2%) were culture positive. Among 50 isolates, 41(82%) were from Early onset septicaemia and 9(18%) were from Late onset septicaemia. The predominant isolate in Early Onset Septicaemia and Late Onset Septicaemia was Klebsiella pneumoniae and Escherichia coli respectively followed by Staphylococcus aureus. Klebsiella showed high resistance to all the antibiotics and was most sensitive to meropenem (82.3%). All other Gram negative bacteria were 100% sensitive to Meropenem, Imipenem and Amikacin.The Gram positive bacteria showed 92% resistance to penicillin and were 100% sensitive to vancomycin and linezolid. Conclusion: In our study, Klebsiella pneumoniae was predominantly isolated. The susceptibility of the bacteria to the commonly used antibiotics was low and needs increased efforts to ensure rational use of antibiotics.
Authors and Affiliations
Mamatha P Samaga, Keerthi B. F, Sini Joseph
Keywords
Related Articles
- EP ID EP426392
- DOI -
- Views 111
- Downloads 0
A Study of Pediatric Long Bone Fracture Treatment using Elastic Titanium Nails
Introduction: various treatment methods are available to treat long bone fractures in children. Method of open reduction involves using intramedullary devices, plates, screws and external fixators. The aim of the present...
Effect of Honey Dressing on Inflammatory Response of Human Dental Pulp after Pulpotmy
Background: Honey has been used as a medicine since ages. In different studies it has been rediscovered by medical professionals in recent times for treatment of burns, infected wounds, and ulcers because of its high ant...
A comparative Clinical Study of Intrathecal Hyperbaric Bupivacaine 0.5% with 25 mg Pethidine Versus 25 mg Tramadol for Infraumbilical Surgeries
Introduction: Requirement of post operative pain relief is mandated due to therapeutic reasons. It was this need of a cost effective but efficient mode of additional post operative analgesia which prompted us to study an...
Study of Level of Total Serum Creatine Phosphokinase as Prognostic Indicator in Acute Organophosphorus Poisoning: A Prospective Study
Introduction: Poisoning has been found to be a major cause of death or morbidity in the developing world, the commonest being Organophosporus (OP) poisoning. Erythrocyte cholinesterase (EchE) and pseudocholinesterase (Bu...
Profile of HIV Seropositive Attendees of Integrated Counseling and Testing Center of a Tertiary Care Teaching Hospital in Kolhapur, India
Introduction: HIV is a multidimensional epidemic and is affected by demographic, socio- cultural, behavioral, economic and biological factors. HIV positive individuals who undergo Voluntary Counseling and Testing are rep...