Bacteriostatic activity of con a lectin from Canavalia ensiformis

Journal Title: Indian Journal of Pharmaceutical and Biological Research - Year 2013, Vol 1, Issue 4

Abstract

The aim of this work was to explore the therapeutic applications of Con A lectin from Canavalia ensiformis and to explore its antibacterial activity. Activity of lectin was quantified by their ability to agglutinate erythrocytes using Hemagglutination assay. Characterization and purity of Con A lectin was evaluated by using SDS-PAGE analysis. The reversal of hemagglutination activity of lectin was evaluated by using the sugars namely; mannose, galactose, lactose, fructose, glucose. The antibacterial activity of lectins was tested against Streptococcus mutans, Staphylococcus aureus, Bacillus subtilis, Escherichia coli using pour plate method. Amoxycillin was used as standard. At 250mg/ml concentration Con A lectin showed good bacteriostatic activity.

Authors and Affiliations

S. R. Kulkarni| Bombay College of Pharmacy, Kalina, Mumbai, India, V. J. Tayade| Bombay College of Pharmacy, Kalina, Mumbai, India

Keywords

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  • EP ID EP13764
  • DOI -
  • Views 362
  • Downloads 20

How To Cite

S. R. Kulkarni, V. J. Tayade (2013). Bacteriostatic activity of con a lectin from Canavalia ensiformis. Indian Journal of Pharmaceutical and Biological Research, 1(4), 59-63. https://europub.co.uk/articles/-A-13764