Behçet’s Uveitis: Current Diagnostic and Therapeutic Approach

Journal Title: Turkish Journal of Ophthalmology - Year 2020, Vol 50, Issue 3

Abstract

Behçet’s disease is a chronic, multisystem inflammatory disorder characterized by relapsing inflammation. Although its etiopathogenesis has not yet been clarified, both the adaptive and innate immune systems, genetic predisposition, and environmental factors have all been implicated. It is more frequent and more severe in males in the third and fourth decades of life. The eye is the most frequently involved organ in the course of the disease. Ocular involvement (Behçet’s uveitis) is characterized by bilateral recurrent non-granulomatous panuveitis and occlusive retinal vasculitis. Recurrent inflammatory episodes in the posterior segment may lead to permanent vision loss due to irreversible retinal damage and complications such as macular scarring, macular atrophy, and optic atrophy. Early and aggressive immunomodulatory treatment and the use of biologic agents when needed are crucial for preventing recurrences and improving visual prognosis.

Authors and Affiliations

Pınar Çakar Özdal

Keywords

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  • EP ID EP684452
  • DOI 10.4274/tjo.galenos.2019.60308
  • Views 183
  • Downloads 0

How To Cite

Pınar Çakar Özdal (2020). Behçet’s Uveitis: Current Diagnostic and Therapeutic Approach. Turkish Journal of Ophthalmology, 50(3), -. https://europub.co.uk/articles/-A-684452