Benefits vs. side effects of Adalimumab treatment in Psoriasis/Psoriatic Arthritis
Journal Title: The Journal of Medical Research - Year 2017, Vol 3, Issue 2
Abstract
Psoriatic Arthritis (PsA) is a seronegative, inflammatory joint disease. In most patients with PSA, skin psoriasis precedes arthritis; however, the causality is multi-factorial and many aspects related to it remain unclear. Tumor necrosis factor (TNF) plays essential role in the pathogenesis of PsA and psoriasis. Hence, the selective inhibition of TNF-α leads to significant improvement of disease activity in patients with immunologically mediated inflammation such as psoriasis and PsA. Adalimumab has been demonstrated to improve functional and dermatological-related limitations. However, not all patients have a good response to Adalimumab, and the long-term safety remains unknown. In this literature review we are highlighting the benefits versus possible side effect of adalimumab in treating psoriatic arthritis and psoriasis.
Authors and Affiliations
Suad Hannawi, Issa Al Salmi
Keywords
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- EP ID EP442584
- DOI 10.31254/jmr.2017.32012
- Views 113
- Downloads 0
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