BENIGN BREAST DISORDERS AND THEIR ASSOCIATION WITH THYROID DISORDERS
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2019, Vol 6, Issue 13
Abstract
BACKGROUND The evidence that breast diseases and thyroid disorders are related is ever increasing. Many recent publications have highlighted the relation of breast cancer to hyperthyroidism. It has led to many institutions screening patients with breast cancer for thyroid disorders. We wanted to find the likelihood of patients with benign breast diseases having thyroid disorders. METHODS This was a case control study conducted in the Department of General Surgery, Pondicherry Institute of Medical Sciences, Puducherry during a period of 18 months from September 2016 to March 2018. Patients who were diagnosed to have breast lesions were categorized as case group (Group A) and patients without breast lesions as control group (Group B). Totally, 48 patients came under case group and 96 patients came under control group. All these patients underwent clinical and laboratory examination to determine their thyroid function status and other thyroid dysfunction that they might have. RESULTS 70.8% of the patients in the case group were categorized as BIRADS category II on mammogram and 29.2% were categorized as BIRADS category III. The most common breast benign disease seen among the patients in our case group was fibroadenosis (60.4%) followed by fibroadenoma (35.4%). Thyroid dysfunction was present in 62.5% and 8.33% of the case and control groups respectively. In the case group, 62.5% of the patients were hypothyroid and 37.5% were euthyroid. In the control group, 6.25% of the patients were hypothyroid and 91.67% were euthyroid. CONCLUSION A patient with a benign breast disease was 18 times more likely to be having thyroid dysfunction as compared to a patient in the control group and this association was found to be statistically significant (p-value<0.01). Also, a patient with benign breast disease was 24 times more likely to be having hypothyroidism as compared to a patient in the control group and this association was found to be statistically significant (p-value<0.01).
Authors and Affiliations
Eldo Varkey George, Jacob Jayakar Raju Mandapati, Ashwin Chand
Keywords
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- EP ID EP615880
- DOI 10.18410/jebmh/2019/222
- Views 95
- Downloads 0
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