Benign Malformative Lesion of the Skull: Hamartoma with Ectopic Elements or Choristoma?

Journal Title: Turkish Journal of Pathology - Year 2017, Vol 33, Issue 3

Abstract

Hamartoma and choristoma are terms that describe non-neoplastic, mass-forming malformative lesions. Although each lesion has a different composition, they have been used interchangeably in many reports, especially for malformative lesions containing ectopic or heterologous elements. We report a three month-old girl who was brought to the clinic with a mass lesion at the posterior fontanel, composed of predominantly osteo-cartilaginous tissue admixed with skeletal muscle, peripheral nerve tissue, and ganglion. The mass was resected completely. The composition of this benign lesion with ectopic elements was consistent with an osteo-cartilaginous hamartoma. We discuss the biological and clinical aspects such malformative lesions within the skull to highlight the inconsistencies of the nomenclature used in the literature.

Authors and Affiliations

Ece MERAM, Hakan KARABAĞLI, Christine GLASTONBURY, Tarik TİHAN, Pınar KARABAĞLI

Keywords

Related Articles

Stem Cell - Is There Any Role in Tumorigenic Activity.

Stem cells are a quintessential key to proper behavior of homeostatic processes. They are often thought of as the solution to a wide range of human conditions, with the ability to rescue malfunctioning or non-functioning...

Multiple Pigmented Seborrheic Keratosis with Sebaceous Differentiation - A Case Report

Seborrheic keratosis is a benign lesion that is common in the trunk and head and neck regions. It shows a considerable variety of histological appearances leading to different variants. The presence of sebaceous differen...

Orthokeratinized Odontogenic Cyst of the Maxilla: Report of a Case and Review of the Literature

The orthokeratinized odontogenic cyst is a relatively rare developmental odontogenic cyst of the jaws that occurs predominantly in males between the third and fourth decades. According to the 2005 World Health Organizati...

Congenital Lobar Emphysema with Pulmonary Extramedullary Hematopoiesis

Congenital lobar emphysema is a one of the rare variety of congenital abnormality of the lung causing respiratory distress in newborns and infants. Herein, we report a case of congenital lobar emphysema in a 3-week-old f...

Uterine adenomyoma of endocervical type: A case report

We report a case of adenomyoma of endocervical type that occurred in a 28-year-old-woman. The patient presented with a mass protruding into vagina which was treated by polypectomy. Histologically, tumor was composed of a...

Download PDF file
  • EP ID EP255253
  • DOI 10.5146/tjpath.2014.01299
  • Views 72
  • Downloads 0

How To Cite

Ece MERAM, Hakan KARABAĞLI, Christine GLASTONBURY, Tarik TİHAN, Pınar KARABAĞLI (2017). Benign Malformative Lesion of the Skull: Hamartoma with Ectopic Elements or Choristoma?. Turkish Journal of Pathology, 33(3), 262-267. https://europub.co.uk/articles/-A-255253