BENZIMIDAZOLE: AS POTENTIAL BIOLOGICALLY ACTIVE AGENT
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2014, Vol 5, Issue 12
Abstract
The benzimidazole ring system is an important pharmacophore in medicinal chemistry and modern drug discovery. Benzimidazole and its derivatives are used in organic synthesis and they are used in evaluating new product that possesses different biological activities. This review article covers the most active benzimidazole derivatives and discusses the structure-activity relationship of the most potent compounds. It can act as an important tool for medicinal chemists to develop newer compounds possessing benzimidazole moiety that could be better agents in terms of efficacy and safety.
Authors and Affiliations
Vikash Chaudhari, Devender Pathak, Satyendra Singh
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The aim of the present study was to evaluate the antidiabetic Potential of ethanol extract of Feronia elephantum Correa leaf and bark in normal and alloxan induced diabetic rats. Diabetes was induced in Albino rats by ad...
DEVELOPMENT AND EVALUATION OF MUCOADHESIVE MICROCAPSULES OF NIMODIPINE
In the present study, the development and evaluation of Mucoadhesive microcapsules of Nimodipine has been undertaken. Nimodipine is a calcium channel blocker used in the treatment of blood pressure, angina pectoris, and...
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This study was designed to investigate the possible adverse effects that may be induced by once-daily therapeutic doses of either glucosamine sulfate or glucosamine/chondroitin sulfate administered orally to rats for 30...
SCREENING OF PHYCOCHEMICAL CONSTITUENTS QUALITATIVELY AND QUANTITATIVELY CERTAIN SEAWEEDS FROM GULF OF MANNAR BIOSPHERE RESERVE
The six seaweeds namely Ulva lactuca (L), Caulerpa racemosa C. Agardh, Sargassum wightii Greville, Padina tetrastomatica Hauck, Gracilaria corticata var. cylindrica J. Ag., and Acanthophora spicifera (vahl.) Boergesen, c...