Better Post Operative Caudal Analgesia With Tramadol Versus Clonidine Added To 0.25% Bupivacaine In Paedeatric Lower Abdominal Surgeries: A Prospective, Randomosed, Double Blind Clinical Study.
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2017, Vol 2, Issue 6
Abstract
In pediatric infra umbilical surgeries, caudal anaesthesia are a preferred mode, however, simple caudal anaesthesia produces analgesia for short duration with very little postoperative analgesia. Addition of some pharmacological agents with local anaesthetics enhances the duration and quality of analgesia. We in our study have compared the efficacy of Tramadol 1 mg/kg or Clonidine 1 mcg/kg with 1 ml/kg of Bupivacaine 0.25% in 60 cases of pediatric infra-umbilical surgeries at Jawaharlal Lal Nehru Medical College & Hospital, Bhagalpur, during the period August 2016 to April 2017. Methods In a randomized. Prospective, double blind study, 60 children from the age group of 1 to 3 years belonging to ASA physical status I and II scheduled for lower abdominal surgeries in different operation theatres of JLNMC&H were included. They were randomly assigned in to two groups. Group I (BT group) (n=30) receiving 1 ml/kg of Bupivacaine) 0.25% with Tramadol 1 mg/kg body weight and group II (BC group (n=30) receiving 1 ml/kg of Bupivacaine with 1 mcg/kg of Clonidine for caudal anaesthesia. Primary variable was the duration of analgesia and the secondary outcome of variables were motor block, sedation score time from caudal blocks to skin incision, emergence time and adverse effects. Results The mean duration of analgesia 632.45 ± 79.39 minutes in-group BT and 740.28 ± 48.25 minutes in-group BC. (p =0.0001). Difference between mean sedation score & mean emergence time between the two groups were statistically significant (p = 0.0001 and 0.0566 respectively). No significant differences were observed in the incidence of hemodynamic changes or adverse side effects. Conclusion Caudal Clonidine with Bupivacaine produces longer duration of postoperative analgesia compared to caudal Tramadol with Bupivacaine in lower abdominal pediatric surgeries with insignificant hemodynamic changes or comparative adverse side effects.
Authors and Affiliations
Dr. Arjun Prasad
Keywords
Related Articles
- EP ID EP530988
- DOI -
- Views 103
- Downloads 0
Prospective Randomised Comparative Study of Screw and Helical blade Proximal Femoral Nail for the Treatment of unstable Intertrochanteric Fractures
Background- Proximal femoral fractures in elderly are usually resulting from minimal to moderate physical trauma to areas of bone significantly weakened by osteoporosis. Methods- This was a Prospective Randomised Compar...
Candidemia in Non-Neutropaenic Patients in a Tertiary Care Centre in South Kerala
Blood stream infections due to candida species cause significant morbidity and mortality especially in the nosocomial setting. The infection is common among the Immuno compromised patients. But it is rare in healthy an...
Case Report – Zinner Syndrome- A Rare Case Report.
Zinner syndrome is a very rare wolfian duct abnormality characterized by congenital unilateral renal agenesis that is absence of one kidney,seminal vesicle cyst and ipsilateral ejaculatory duct obstruction . The conditio...
A Study on Morphometric Analysis of Sacral Vestibule Using Plain Computed Tomography
Background- The present study was aimed to study and develop in-depth understanding of the morphometry of sacral vestibule in North-West Indian population presenting to our institution, which will go a long way in planni...
Verrucous Hemangioma in an Adult: Report of a Rare Case
Verrucous hemangioma is a rare congenital vascular malformation. It usually occurs at birth, but can appear later in adulthood. Clinically it presents as well demarcated papules, plaques or nodules of bluish- red colour...