Bioactive molecule of essential oil of Cuperssus sempervirence Mill – in vitro other treatment against microbial pathogenesis
Journal Title: UNKNOWN - Year 2018, Vol 2, Issue 1
Abstract
Background: Each year, many million people attract infections caused by bacteria, fungi, virus,and parasite, infectious diseases reached at high rate, and the problem of emerging and reemerginginfections becomes a serious danger to human health, medicinal plants constitute asource of bioactive molecules can fight against infection microbial disease. In the context of thisresearch, was intended to characterize biomolecule of hydro-distilled essential oil of Cuperssussempervirence produces in west of Algeria and its potentials against disease infections.Methods: The essential oil was analyzed by gas chromatography-mass spectrometry (GC-MS)method and Antibacterial activity was investigated in vitro against twelve clinical and referenceencountered in Clinical Laboratory and the Microbiology Laboratory of Saidal Medea using thewell diffusion method. The minimum inhibitory concentration (MIC) and minimum bactericidalconcentration (MBC) were determined by the dilution method agar.Results: The most common components usually found in cypress essential oils were present in theoil samples analyzed, 43 components, which constitute 97,893% were identified in the essentialoil. The major constituents were Alpha pinene (60.05%), delta-3-carene (18.08%) et terpinolene(2.44%). myrcene (2.39%), limonene (1.83%), the results of the disk diffusion method showedhigh essential oils activity against all strains tested . The best antimicrobial activity againstCandida albicans ATCC1231was found (0.001v/v) .Bactericidal activity was higher for EO(minimal inhibitory concentration (MICs) 0.02(v/v)) against almost all tested bacteria, exceptmulti drug resistant strains of Salmonella typhimiruim ATCC13311 and Bacillus cereusATCC10876. The results obtained of this study provide that essential oil of Cuperssussempervirence is treatment against microbial pathogenesis human.
Authors and Affiliations
Hadjer BOUDJEMAA, Rachida ALLEM, Salem Belkessa
Keywords
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- EP ID EP648619
- DOI 10.26415/2572-004X-vol2iss1p196-196
- Views 37
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