Biochemical Characteristics and Clinical Significance of Il-35: A Review Article
Journal Title: International Journal of Health & Medical Research - Year 2024, Vol 3, Issue 12
Abstract
IL-35 belongs to the IL-12 family of cytokines that are involved in immune-regulation and homeostasis. It generally features as a heterodimeric cytokine composed of IL-12p35 and EBV-induced gene 3, mainly secreted by regulatory T cells and B cells within the human body. Therefore, IL-35 is known to have enormous immune-suppressive abilities. This paper thus provides the existing insights over the biochemistry and pathophysiology of IL-35 concerning inflammation, microbial infections, carcinogenesis, as well as autoimmune disorders, meanwhile intending to identify lacunae and suggest prospective lines of research.
Authors and Affiliations
Amany Menam Mtsher, Noor A. Raheem, Ali A. Al-fahham,
Keywords
Related Articles
- EP ID EP761545
- DOI 10.58806/ijhmr.2024.v3i12n06
- Views 14
- Downloads 0
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