Biochemical Description of the Systemic Inflammatory Response in infants after Severe Birth Asphyxia
Journal Title: Здоров`я дитини - Year 2014, Vol 1, Issue 52
Abstract
This article presents the results of a study of biochemical indicators of systemic inflammatory response in infants after severe birth asphyxia. In a group of 34 newborns there were determined the indicators of inflammation: interleukin-6, interleukin-1β, interleukin-4, tumor necrosis factor α and the level of weighted average molecules. The study revealed that the course of systemic inflammatory response in recovered infants was caused by the activation of anti-inflammatory cytokine interleukin-4, which may have prevented the progression of systemic inflammatory response and the development of endogenous intoxication. The course of systemic inflammatory response in died neonates was characterized by activation of anti-inflammatory as well as pro-inflammatory cytokines with the simultaneous development of endogenous intoxication and abrupt inhibition of cytokine synthesis against the progression of endogenous intoxication on the 7th day of life.
Authors and Affiliations
S. S. Ovcharenko, N. M. Mezhirova, G. D. Kravtsova
Keywords
Related Articles
- EP ID EP306295
- DOI -
- Views 63
- Downloads 0
Prebiotic Properties of Carbohydrates in the Formation of Children’s Health
Сontent of dietary fibers, pectin and fibers in modern products is studied. The necessity for dysbiosis prevention is established on the basis of prebiotic properties of carbohydrates providing a synthesis of metabolites...
Hyperuricemia in Destabilization of Endothelial Function in Adolescents with Arterial Hypertension
The objective of this work was to study the correlation of uric acid level in blood serum and parameters of endothelial function and non-specific inflammation in adolescents with arterial hypertension considering their b...
Stevens-Johnson syndrome in an adolescent: diagnosis and treatment (clinical case)
The authors present a clinical case of Stevens-Johnson syndrome in an adolescent, a resident of Ternopil region, who was hospitalized in the intensive care unit of Ternopil Regional Children’s Clinical Hospital. The feat...
Surgical Correction of Inguinal Hernias in Children Using Minimally Invasive PIRS Method
Introduction. Inguinal hernia (IH) — one of the most common childhood diseases that requires surgical treatment. The main indication for surgical treatment of IH is a risk of its strangulation. Among the methods of lapar...
Glycine encephalopathy in newborns and young children: global management standards and a clinical case
The article shows a three-level approach to the diagnosis of glycine encephalopathy by the example of a clinical case. The article considers the modern etiology of the disease, based on molecular genetic testing of biall...