Biochemical parameters of metabolic syndrome in type 2 diabetes patients: retrospective study
Journal Title: Current Issues in Pharmacy and Medical Sciences - Year 2013, Vol 26, Issue 4
Abstract
Metabolic syndrome is one of the most important problems of public health in developed societies. A constant interest in this issue is caused by a wide spread of this problem and the lack of uniform diagnostic criteria. The variety of functioning definitions make fast algorithm difficult for a diagnostician, thus the aim of this study was to check the relationship between presence of selected biochemical indicators of metabolic syndrome in a large group of patients with diabetes type 2, and the differences in the course of the disease and degree of compensation. For this comparison, we have used World Health Organization and the National Cholesterol Education Program Adult Treatment Panel III criteria of metabolic syndrome. The studies were performed among 1079 patients with diagnosed diabetes type 2. It is worthwhile that triglycerides elevation in diabetic patients could be treated as a sensitive and specific indicator of metabolic syndrome presence even without evaluation of other features. This observation finds intermediate confirmation also in our study; however, future studies are needed to examine the significance of metabolic syndrome following all criteria for the assessment of risk for diabetes and/or cardiovascular disease.
Authors and Affiliations
Dariusz Chlebus, Iwona Kaznowska-Bystryk, Halina Lewandowska-Stanek, Magdalena Hałabiś
Investigation of the hepatoprotective properties of “Phytovenol” capsules on the model of medicamentous hepatitis in rats
This scientific paper is an investigation of the pharmacological activity of the new medical preparation “Phytovenol” (capsules in the dose of 150 mg/kg) on the pattern of hepatitis in rats induced by paracetamol adminis...
Comparison of two molecular docking programs: the accuracy of ligand pose prediction
The study was perform to compare the output of two different docking programs (Molegro Vritual Docker and AutoDock) in simulation of ligand-receptor interactions for β1 and β2 adrenergic receptors. The exactness of the p...
Monitoring of liver function in patients with fatty liver disease in combination with coronary heart disease and type 2 diabetes
The aim of the study was to examine the liver detoxification function by comparing a 13C- methacethine breath test, with a Forns formula and with liver transaminases in patients with coronary heart disease and type 2 dia...
Simultaneous determination of amlodipine and telmisartan from pharmaceutical products by way of capillary electrophoresis
A rapid, simple and sensitive capillary zone electrophoresis method was developed for the simultaneous determination of amlodipine besylate and telmisartan, in fixed-dose combinations, through the utilization of a UV pho...
Ànalgesic and anti-inflammatory activities of traditional mongolian drug Garidi-5
Garidi-5, a traditional medicine composed of 5 herbs including Terminalia chebula Retz., Aconitum Kusnezoffii Reichb., Acorus calamus L., Saussurea lappa L., and musk of Moschus moschiferus, has been used in traditional...