Biochemical regulation of condylar growth and remodelling – An overview
Journal Title: IP Indian Journal of Orthodontics and Dentofacial Research - Year 2018, Vol 4, Issue 3
Abstract
Condylar cartilage has been classified as an articular cartilage It has been further categorized as a secondary cartilage This characterization is based upon its delayed development unique histological features and adaptive capability to external stimuli This adaptive and remodelling capacity of condylar cartilage to forward positioning of mandible forms basis of orthodontic functional treatmentMolecular and genetic control of epiphyseal cartilage has been well documented However condylar cartilage has received attention only in last few decades Condylar cartilage growth has partial genetic and strong epigenetic control Epigenetic control includes systemic factors and local factors such as growth factors and mechanical stimuli Various growth factors and transduction mediators bring about natural development and adaptive remodelling of condylar cartilage Growth factors are large group of polypeptide molecule which exerts its effect by paracrine or endocrine mechanism Growth factors can exert various effects depending on the type of receptor it interacts Depending upon the receptor it can bring about mitotic hypertrophic or anti proliferative effect These molecular controls play important role in growth and homeostasisThis article is an attempt to assimilate available knowledge and current concept regarding molecular and genetic control of condylar growthKeywords Condylar growth Remodelling Growth factor
Authors and Affiliations
Tulika Tripathi, Vikash Kumar, Shilpa Kalra, Priyank Rai
Keywords
Related Articles
- EP ID EP514532
- DOI 10.18231/2455-6785.2018.0027
- Views 79
- Downloads 0
Comparative assessment of bone stress associated with miniplates and mini-implants used for orthodontic anchorage: A finite element study
Objective: To assess and compare bone stress associated with various miniplates and mini-implant systems by using finite element analysis. Materials and Methods: Bone stress associated with various miniplate and mini-imp...
Clear aligners in orthodontics
When we hear the word orthodontics what comes to mind is probably a young teenager whose teeth are covered by a latticework of metal However there now exists an increasingly popular alternative to traditional metal brace...
Reliability of Moyers and Tanaka Johnston Mixed Dentition analysis in school children of Belgaum
Context: The accuracy of Moyers proportionality tables and Tanaka and Johnston equations are fairly good when applied to children from northern European descents from which data were originally obtained. Because racial d...
Clinical effects of different antiplaque agents on patients undergoing fixed orthodontic treatment- A comparative study
Objectives: The purpose of this study was to compare the short-term clinical effects of a Chlorhexidine mouth wash (CHX-MW), Chlorhexidine gel (CHX), Metronidazole gel (MTZ) and combination of Chlorhexidine and Metronida...
Psycho-social effects of malocclusion in patients seeking orthodontic treatment- A cross-sectional study in Kashmiri population
Introduction: While treating a patient with malocclusion most of the focus is directed towards chief complaint, biomechanics, materials to be used, majority of the times ignoring the pre and post treatment psychological...