Biological activity and phytochemical screening of different extracts of Sida cordata (Burm.F.) borssum root
Journal Title: IP International Journal of Comprehensive and Advanced Pharmacology - Year 2018, Vol 3, Issue 1
Abstract
In the present study was designed to evaluate antimicrobial anthelminthic activity and phytochemical analysis of different extracts of Sida cordata Burm f borssum root rxtract was prepared using different solvents like chloroform petroleum ether ethylacetate ethanol and water aqueous extract By using agar well diffusion method the antibiotic activity of different extract was evaluated and minimum inhibitory concentration MIC by 96 well resazurin based microtiter dilution the test organisms were Escherichia coli Staphylococcus aureus Lacto bacillus Pseudomonas aeroginosa Candida albicans Aspergillus niger Among the different the extracts ethanolic and aqueous showed significant antimicrobial activity against Staphylococcus aureus Escherichia coli Lacto bacillus Pseudomonas aeroginosa Candida albicans and Aspergillus niger Against Saureus aqueous extract showed better activity 20mm MIC 0187 mgml followed by Ethanol extract 15mm with MIC 0390 mgml further the aqueous extract showed activity against Pseudomonas aeruginosa 15mm MIC 15 mgml followed by Ethanol extract 12mm with MIC 0375 mgml and same was observed for Lactobacillus 19mm In terms of anthelmintic activity against Pheretima posthuma Indian earthworm aqueous extract of the root exhibited significant activity in the concentration of 100mgml with 220 and 39 minutes for paralysis and death respectively and that of standard drug Albendazole was 20 and 3800 minutes The aqueous extract showed significantly better effect comparable to standard and hence higher anthelmintic activityKeywords Sida cordata Antimicrobial Resazurin Anthelminthic Pheretima posthuma
Authors and Affiliations
Gulnaz. A. R, Sumaya Thabassum, Md. Salahuddin, Savitha. G
Keywords
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- EP ID EP481705
- DOI 10.18231/2456-9542.2018.0005
- Views 84
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