Biological Analysis and Phytochemical Studies of The Exocarp Fruits Extracts of African Star Apple (Chrysophyllum albidum G. Don)
Journal Title: Scholars Academic Journal of Pharmacy - Year 2014, Vol 3, Issue 5
Abstract
The exocarp of the fruit extracts of Chrysophyllum albidum was extracted using hexane and ethyl acetate. This study was carried out to investigate the phytochemicals and to also test for antimicrobial activity. These extracts were tested against some gram-negative organisms (Escherichia coli, Klebsiella pneumonia) and gram-positive organism (Staphylococcus aureus) using disc diffusion and micro broth dilution techniques with the disc concentration 60 µg/disc. The entire organisms were sensitive to ethyl acetate extract of the plate at 30 µg/disc concentration as follows; E. coli (9 mm), Klebsiella spp. (9 mm) and Staphylococcus spp. (11 mm). E.coli and Staphylococcus spp. were insensitive in the hexane extract and they were not inhibited. Except Klebsiella spp. that is sensitive at a disc concentration of 60 µg/disc with zone of inhibition diameter of 9mm.The result of phytochemical studies of both extracts show the presence of alkaloids, saponins, steroids, tannins and volatile oil but saponins and tannins are absent in the hexane extract. Keywords: Chrysophyllum albidum, gram-negative organism, gram-positive organism, phytochemical, zone of inhibition. .
Authors and Affiliations
Orijajogun O. Joyce, Olajide O. Olutayo, Useh U. Mercy
Keywords
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