BIOLOGICALLY ACTIVE SECONDARY METABOLITES FROM KALANCHOE TOMENTOSA
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2014, Vol 3, Issue 6
Abstract
Phytochemical study of the ethanolic extract of Kalanchoe tomentosa (Crassulaceae) resulted in the isolation of 14 compounds identified as; α-amyrin acetate (1), friedelin (2), glutinol (3), 1-dotriacontanol (4), phytol (5), Stigmasta-7,25-dien-3β-ol (6), β-sitosterol (7), Isorhamnetin (8), 2,3-dihydroxypropyl tetradecanoate (9), Eriodictyol (10), Gallic acid (11), quercetin (12), kampferol-3-O-Rutinoside (13) and isovitexin (14). These compounds were isolated for the first time from this species. The structure elucidation of isolated metabolites was carried out using spectroscopic data (1D and 2D NMR). Antioxidant, cytotoxic and antimicrobial activities of different plant extracts were also studied and significant results were obtained.
Authors and Affiliations
Mostafa M. Saleh| Department of Pharmacognosy, Faculty of Pharmacy, The University of Al-Azhar, Cairo 11371, Egypt., Mohammed M. Ghoneim| Department of Pharmacognosy, Faculty of Pharmacy, The University of Al-Azhar, Cairo 11371, Egypt., Saeid Kottb| Department of Pharmacognosy, Faculty of Pharmacy, The University of Al-Azhar, Cairo 11371, Egypt., Atef A. El-Hela*| Department of Pharmacognosy, Faculty of Pharmacy, The University of Al-Azhar, Cairo 11371, Egypt.
Keywords
Related Articles
- EP ID EP3473
- DOI -
- Views 384
- Downloads 15
“A Large Incidentally-Diagnosed Left-Lobed Hepatic Hydatid Cyst in a Young Male Patient”
Introduction: Despite modern healthcare facilities, hydatid disease (HD) remains a perpetuating public health problem in endemic countries. Infection with Echinococcus may have a diverse clinical evolution, leading even...
SYNTHESIS AND CHARACTERIZATION OF SOME METAL COMPLEXES WITH IBA AS LIGAND DERIVED FROM 2–BENZOYLINDANE–1,3–DIONE
The present investigation are based on the synthesis and characterization of metal complexes with Schiff’s bases α– (1, 3– dioxo– indan– 2–yl) – benzylidene– aniline (IBA) derived from 2–Benzoylindane–1,3–Dione by cond...
Pharmacognostical, Phytochemical, Pharmacological and Toxicological Review on Trichosanthesanguina Linn
Traditional medicine is widely spread globally and it is the almost exclusive source of primary health care for 80% of the world’s population. Herbal medicines are regarded by the public and some health care providers to...
COMPARISON OF THE THERAPEUTIC ACTIONS OF TAURINE, METHYLSULFONYLMETHANE AND SILYMARIN AGAINST ACETAMINOPHEN-INDUCED NEURO- AND HEPATO-TOXICITY IN ADULT MALE ALBINO RATS.
To evaluate the neuro- and hepato-curative effects of taurine (TAU) and methylsulfonylmethane (MSM) in acetaminophen- induced neuro- and hepato- toxicity in adult male albino rats. Silymarin (SLN) was used as reference d...
ELECTROCHEMICAL PEROXIDASE SENSOR BASED ON MAGNESIUM OXIDE-CHITOSAN NANOBIOCOMPOSITE FILM
Nanoparticles play a major role in development of new hybrid composites for various engineering applications. A simple and novel amperometric biosensor for hydrogen peroxide detection is proposed. It is based on the immo...