BIOLOGICALLY ACTIVE SECONDARY METABOLITES FROM KALANCHOE TOMENTOSA
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2014, Vol 3, Issue 6
Abstract
Phytochemical study of the ethanolic extract of Kalanchoe tomentosa (Crassulaceae) resulted in the isolation of 14 compounds identified as; α-amyrin acetate (1), friedelin (2), glutinol (3), 1-dotriacontanol (4), phytol (5), Stigmasta-7,25-dien-3β-ol (6), β-sitosterol (7), Isorhamnetin (8), 2,3-dihydroxypropyl tetradecanoate (9), Eriodictyol (10), Gallic acid (11), quercetin (12), kampferol-3-O-Rutinoside (13) and isovitexin (14). These compounds were isolated for the first time from this species. The structure elucidation of isolated metabolites was carried out using spectroscopic data (1D and 2D NMR). Antioxidant, cytotoxic and antimicrobial activities of different plant extracts were also studied and significant results were obtained.
Authors and Affiliations
Mostafa M. Saleh| Department of Pharmacognosy, Faculty of Pharmacy, The University of Al-Azhar, Cairo 11371, Egypt., Mohammed M. Ghoneim| Department of Pharmacognosy, Faculty of Pharmacy, The University of Al-Azhar, Cairo 11371, Egypt., Saeid Kottb| Department of Pharmacognosy, Faculty of Pharmacy, The University of Al-Azhar, Cairo 11371, Egypt., Atef A. El-Hela*| Department of Pharmacognosy, Faculty of Pharmacy, The University of Al-Azhar, Cairo 11371, Egypt.
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