Biomarker Development for Brain-Based Disorders: Recent Progress in Psychiatry
Journal Title: Journal of Neurology and Psychology - Year 2013, Vol 1, Issue 2
Abstract
Biomarkers are biological measures that are indicative of a specific disorder, its severity or response to treatment. They are widely used in many areas of medicine, but biomarker development for brain-based disorders lags behind. Using examples from the field of psychiatry, this article reviews the concepts of biomarkers, challenges to their development and the recent progress along those lines. In addition to discussing historical biomarker candidates such as cortisol or catecholamine levels, we include progress from recent genetic, epigenetic, proteomic, neuroimaging and EEG studies. Successful identification of biomarkers will advance the field of psychiatry towards the goal of biological tests for diagnosis, symptom management and treatment response.
Authors and Affiliations
Alicia K. Smith
Moving Fingers Moving Toes: A Heterogeneous Entity
Painful legs and moving toes is a rare movement disorder. It can be associated with peripheral neuropathy, trauma, radiculopathy or autonomic disturbances. Variants of the phenomenon involving fingers and arms, with or w...
Subjective Sleep Quality in Iranian Patients with Spinal Cord Injury: Results of Pittsburgh Sleep Quality Index in a Referral Center
Background: Sleep quality is an important factor influencing quality of life in patients with spinal cord injury (SCI). Our purpose was to evaluate and report sleep quality in Iranian individuals with SCI in a referral c...
Investment in Treatment of Psychological Disorders Could Save Money
In this editorial we will explain how investment in treatment of psychological disorders could save overall cost. We will give the example of a common psychological disorder which is addiction. Addiction to prescription...
Koro-Like Syndrome in an Iranian 50 Years Old Man; Is It A Variant Caused by Cultural Issues?
Koro syndrome is a psychiatric disorder characterized by acute anxiety of one’s genital retraction. In this culture-bound syndrome, originally reported in south and East Asia, the male individual believes that his penis...
Interpersonal Psychotherapy Efficacy in Different Clinical Settings
Interpersonal therapy is an effective brief and limited therapy originally developed for major depression disorder but nowadays also highly effective in other psychiatric disorders [1,2]. This therapy uses the biopsychos...