Biphasic Variant of Clear Cell Odontogenic Carcinoma - A Case Report
Journal Title: Interventions in Pediatric Dentistry Open Access Journal - Year 2018, Vol 1, Issue 1
Abstract
Clear cell odontogenic carcinoma (CCOC) is a rare neoplasm of the jaw. This report outlines the clinical, histopathological and immuno-histochemical findings of CCOC and describes management strategy according to experience of authors and review of literature. We present a case of CCOC in a 70 years old female at posterior region of mandible. Microscopically, this tumor consisted of nests of cells with eosinophillic cytoplasm, small oval nuclei and a few clear cell areas. Treatment comprised of wide local excision and modified radical neck dissection with no recurrence. Clear cell odontogenic carcinoma (CCOC) is a rare intraosseous carcinoma of the jaw described in 1985 for the first time by Hansen [1]. In 1992, WHO classified CCOC as benign odontogenic tumor however, in the WHO classification of 2005 it was considered to be a malignant tumor of odontogenic origin due to its aggressive nature, predilection to local recurrence, loco-regional lymph node metastasis and distant metastasis [2]. Only 82 cases have been reported until now excluding the present case [3]. In this study, we report an additional rare case of CCOC extending from the left premolar area to the left ascending ramus of mandible and discuss the previous literatures.
Authors and Affiliations
Sufyan Ahmed, Syeda Hala Raza, Haider Ali
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