Bisphophonates and dental Implants – A literature review
Journal Title: IP Annals of Prosthodontics and Restorative Dentistry - Year 2017, Vol 3, Issue 2
Abstract
Osteonecrosis of the jaw has been described in patients taking bisphosphonates after oral surgery procedures, including the placement of dental implants. The success of these procedures depend on the fixation of the implants which, in turn depends on the strength of the bone that holds them. Bisphosphonates are anti-resorptive drugs that act specifically on osteoclasts, thereby maintaining bone density and strength. These drugs inhibit bone resorption and are used to treat a range of pathologies, including Paget disease, osteoporosis, multiple myeloma and metastases associated with breast or prostate cancer. At present, there is no effective treatment for bisphosphonate induced osteonecrosis, so prevention is extremely important. Since quality of life deteriorates for those suffering osteonecrosis, maximum precautions should be taken with patients at risk. The aim of this study was to conduct a systematic review in order to evaluate whether patients on BP therapy are appropriate candidates for dental implants as compared to patients not taking BP drugs with respect to successful implant osseointegration and the risk of developing bisphosphonaterelated osteonecrosis of the jaw.
Authors and Affiliations
Rahul Sharma, Dhruv Anand, Ashish Choudhary, Jay Vikram, Anurag Hasti
Keywords
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- EP ID EP311103
- DOI 10.18231/2455-8486.2017.0014
- Views 60
- Downloads 0
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