Bladder Cancer in Iran: Geographical Distribution and Risk Factors
Journal Title: International Journal of Cancer Management - Year 2017, Vol 10, Issue 2
Abstract
Background To study overall and province-specific trends of bladder cancer incidence in Iran during 2004-2008 and to evaluate the association between bladder cancer incidence and some factors. Methods Data on 17792 bladder cancer patients and risk factors available at province level were used in Bayesian ecological setting. First, the overall and province-specific trends of risk were estimated. Then the effects of cigarette smoking, being overweight, fruits and vegetables consumption, and low levels of physical activity on trend were examined. The province-specific effects of significant factors were also assessed. The data were analyzed using R-INLA package. Results The risk of developing bladder cancer was decreasing in Iran, 2004 - 2008 (RR = 0.95). Guilan and Semnan had the highest 5-year incidence (RR > 1.5). However, the risk increase compared to country Risk was the highest in East Azerbaijan and Tehran (DT > 0.1). Also direct and reverse association between smoking and fruit consumption and bladder cancer risk were established. Guilan, Semnan, Sistan and Baluchestan, and Ilam were the provinces affected the most by these factors. Conclusions This study confirms previous findings and provides further evidence on protective effects of fruit consumption in bladder cancer. The results would be of value for governors to prioritize the province-specific demands on research, education, and improvements with respect to the identified risk factors.
Authors and Affiliations
Tohid Jafari-Koshki, Shahram Arsang-Jang, Behzad Mahaki
Keywords
Related Articles
- EP ID EP237295
- DOI 10.5812/ijcp.5610
- Views 59
- Downloads 0
Anti-Proliferative Effects of Piroxicam and Nimesulide on A431 Human Squamous Carcinoma Cell Line
Background Skin cancer is one of the most common types of cancer worldwide and non-steroidal anti-inflammatory drugs (NSAIDs) have been proposed for prevention and treatment of a...
Production of Specific Anti-EGFR Single Chain Antibodies: A Promising Strategy in the Immunotherapy of EGFR Expressing Tumor Tissues
Background: EGFR (Epidermal growth factor receptor) is overexpressed in a number of cancers and plays an important role in several phenomena such as aggressiveness of tumor, decreased survival of the patient, and resista...
Antioxidant Supplements and Breast Cancer: A Systematic Review and Meta-Analysis
Context: Breast cancer is the second most common type of cancer worldwide and the most frequent one among women. Some studies suggest a favorable role of antioxidants on breast cancer, but this is still controversial. O...
Prognostic Factors and Survival of Glioblastoma Multiform (GBM) in Iranian Patients
Background Glioblastoma Multiform has been a common and fatal brain tumor. In this regard, there was ambiguity around patient survival rates in Iran que to data insufficiency. In...
A Comparative Study of FIGO 1988 Versus 2009 Staging for Endometrial Carcinoma
Objectives: The aim of this study was to investigate the benefits of the newly revised “The international federation of gynecology and obstetrics (FIGO), 2009” sytem and whether there was a difference in new system compa...