Bleeding Diathesis: When Do We Suspect Vitamin B12 Deficiency?
Journal Title: Journal of Medical Science And clinical Research - Year 2016, Vol 4, Issue 3
Abstract
Megloblastic anemia is uncommon in pediatric age group. It is most commonly due to vitamin deficiencies or gastrointestinal disorders. Megaloblastic anemia due to Dietary vitamin B-12 deficiency in infants is very rare but may be seen in breastfed infants whose mothers are B-12 deficient. Sometimes absence of carrier protein, transcobalamin, may present with megaloblastic anemia in early infancy. These infants if not treated promptly may develop myelopathy and developmental delay. Other children may sometimes present with bleeding diathesis secondary to qualitative and quantitative defects of platelets and sometimes pancytopenia. We present here a case of 8 year old girl who presented to us solely with ecchymosis and subcutaneous haematomas. Her blood picture showed bicytopenia with high MCV pointing towards the diagnosis of Megaloblastic Anemia. Bone marrow biopsy confirmed the diagnosis. She was given intramuscular methylcobalamine for 2 weeks followed by oral methylcobalamine and folic acid.
Authors and Affiliations
Dr Sushant Mane
Keywords
Related Articles
- EP ID EP213414
- DOI -
- Views 96
- Downloads 0
Limited Sclerosis- A Rare Connective Tissue Disorder- A Case Report
Limited cutaneous scleroderma is a rare connective tissue disorder characterised by thickening of skin limited to the distal aspect of limbs and face and the basic pathology is functional and structural vascular alterati...
Dextrose Treats Optic Neuritis
The sphenopalatine ganglion—also known as pterygopalatine ganglion, Meckel’s ganglion, Sluder’s ganglion and nasal ganglion—is the largest of the four parasympathetic ganglia associated with the trigeminal nerve. It is c...
Influence of Family Dynamics on Medication Adherence among Hypertensive Patients in a Tertiary Hospital in South-West Nigeria
Hypertension is an overwhelming global challenge estimated to cause 7.5 million death, which is about 12.8% of all deaths. 1 The emerging pandemic of non-communicable diseases (NCDs) is creating major health challenges w...
A study on safety and efficacy of Deferasirox, an oral iron chelator in the treatment of transfusion haemosiderosis in children with β-Thalassemia Major in a tertiary care rural hospital
Background: β-Thalassemia major is a hereditary hemolytic anaemia (and the commonest transfusion dependent anaemia) which continues to be a major cause of morbidity and mortality in developing countries like India. Defer...
Frequency of HBV and HCV among Patients Undergoing Elective Surgery in a Tertiary Care Referral Hospital in Duhok, Iraqi Kurdistan
Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections possess occupational hazard to health care workers (HCWs) particularly surgeons, anesthetists, nurses and theater staff. Reliable epidemiological data on fre...