Bleeding Risk under Oral Factor Xa Inhibitors: Meta-analysis of the randomized comparison with Vitamin K Antagonists and Meta-Regression analysis
Journal Title: Journal of Cardiovascular Medicine and Cardiology - Year 2017, Vol 4, Issue 3
Abstract
Background: Randomized trials have shown that oral direct factor Xa inhibitors (ODIXa) offer potential advantages over vitamin K antagonists (VKAs). It is however unclear whether the magnitude of their benefit is similar at the current recommended doses. Objective: We assessed bleeding risks and total mortality associated with ODIXa therapy compared to VKAs among patients with non-valvular atrial fibrillation or acute venous thromboembolic disease.
Authors and Affiliations
Nabila Ferahta, Lukshe Kanagaratnam, Moustapha Dramé, Thomas Vogel, Pierre-Jacques Ambrosi, Pierre-Olivier Lang
Keywords
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- EP ID EP232070
- DOI 10.17352/2455-2976.000048
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