Blood Sugar & Vitamin B12 Level in Psoriasis Patients in Relation to Diabetes Mellitus and Hyper Tension
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 4
Abstract
Background: Psoriasis is a chronic disfiguring inflammatory and proliferative condition of the skin in which both genetic and environmental influences have a critical role. Several reports have shown an increased risk for the metabolic syndrome (a combination of central obesity, DM Type 2 or insulin resistance, Hyper Tension and combined hyperlipidemia) in patients with psoriasis, but there are few Indian studies on the association between psoriasis with diabetes and hypertension together. Objective: To study blood sugar and serum B12 level at the beginning of study and after 8 weeks in 2 groups of Psoriasis patients. Method: A cross-sectional study was performed in 300 clinically diagnosed Psoriasis patients (Group II) which were further grouped as 200 plain psoriasis (Group IIA) and 100 psoriasis cases with DM or DM and HT both (Group IIB) and 200 age and gender matched healthy subjects as the controls(Group I). Blood sugar and serum Vit. B12 level were measured at the beginning of study and after 8 weeks in both the groups. Result: Patient presented no significant change in the blood glucose level in Group IIA psoriasis patients at the beginning of study and after 8 weeks as compared to controls but in Group IIB psoriasis there is significant increase (P<0.01) at the beginning but after 8 weeks its value is increased highly significantly (P<0.001) as compared to controls. Serum B12 level is decreased and increased significantly (P<0.01) in Group IIA psoriasis patients at the beginning and after 8 weeks respectively. But in Group IIB psoriasis patients its value is decreased and increased highly significantly (P<0.001)at the beginning of study and after 8 weeks which shows that B12 level is lower in psoriatic skin than in non-psoriatic skin and active lesions had lower level than healed lesions. Conclusion: Data suggests that psoriatic patients must be considered as a group at high risk for becoming diabetic due to high Blood sugar level and more prone for cardiovascular disease due to low serum B12 level in psoriatic skin than in non-psoriatic skin.
Authors and Affiliations
Payasvi Baweja
Keywords
Related Articles
- EP ID EP211325
- DOI -
- Views 68
- Downloads 0
Neuropsychiatric Manifestation in HIV/AIDS
Aim: To study the neuropsychiatric manifestations in patients with HIV / AIDS. Design: Cross – sectional study Methods: 50 male & female HIV positive / AIDS patients in the age range of 18-60yrs of age without any past p...
Versatality of Limberg Flap
Background: Pilonidal sinus is a relatively common condition affecting men twice as often as women. Decubitus ulcer is more prevalent in elderly and mainly at sacral region. The management of pilonidal sinus disease or s...
Evaluation of Wound Healing Activity of Leaves of bombax Ceiba
Bombax Ceiba, commonly known as Silk cotton tree, is used in folklore medicine in Diabetics, Hypertension, as analgesics, leucorrhoea, sealing of secondary infection, healing of wounds and skin eruptions. There was no sc...
Comparative Effect of Kinesiotape and Rigid Tape with Therapeutic Putty Exercise on Pinch Strenght in Instrumentalists – A Randomized Clinical Trial
Study objectives- The purpose of this study was to investigate the comparative effect of kinesio tape and rigid tape with therapeutic putty exercises on pinch strength in instrumentalists. Design- Comparative study Setti...
Ultrasound Guided Fine needle aspiration Cytology evaluation of Solitary Thyroid Nodule – One year study
Background: Ultrasound guided Fine needle aspiration Cytology decrease is a useful technique with minimum invasion and complication. Objectives: To evaluate of solitary thyroid nodule by Ultrasound guided Fine needle asp...