BLOOD TRANSFUSION ADVERSE REACTIONS, INCIDENCE AND CAUSES- A RETROSPECTIVE STUDY OF 3 YEARS AT A TERTIARY CARE HOSPITAL IN HYDERABAD
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2018, Vol 5, Issue 42
Abstract
BACKGROUND Blood transfusion is the transfusion of whole blood or blood components (packed cells or plasma only) into the blood stream or directly into the bone marrow. 1 It is carried out between individuals with compatible / identical blood groups, failure of which results in adverse transfusion reactions. An ATR (Adverse Transfusion Reaction) is an unfavourable reaction to the transfused blood/ blood component, the severity of which differs from person to person depending on the patient’s susceptibility, degree of incompatibility and the type of reaction. 2 MATERIALS AND METHODS Transfusion reactions may be immediate or delayed type in onset. It can be immune or non-immune type depending on pathogenesis. The study was conducted at Gandhi Hospital blood bank which is a tertiary multispecialty hospital, for a period of three years from 2015 to 2018, with emphasis on incidence and manifestations of various transfusion reactions and associated morbidity. A total of 60,950 transfusion units were transfused during the period of August 2015 to August 2018, out of which 11 cases reported with ATR. RESULTS During the study, adverse transfusion reactions were recorded for 11 patients, with chills and rigors in 4 cases constituting 45.5% of the cases, shortness of breath was observed in 3 cases, accounting to 27.4%, fever was found in 2 cases with 18.1% and rash was observed in 2 cases with 9%. CONCLUSION Hemovigilance and practice of safe blood transfusion along with documentation and due prevention minimise the ATR’s incidence considerably.
Authors and Affiliations
Padmamalini K. , Shrinivas Bheemrao Somalwar, Sudha Sudha, Shravan Kumar O.
Keywords
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- EP ID EP598898
- DOI 10.18410/jebmh/2018/604
- Views 78
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