Bony Secondaries and Dissemination in Advance Carcinoma Gallbladder: A Longitudinal Study
Journal Title: Clinical Radiology & Imaging Journal - Year 2018, Vol 2, Issue 3
Abstract
1.1. Context: Metastasis in carcinoma gall bladder is uncommon and occurs late in the course of the disease. Of all the distant sites that can be involved, the skeletal system is the least common site. We hereby present a prospective longitudinal study depicting the incidence, type, predisposing site and time of presentation of skeletal metastasis in carcinoma gallbladder. 1.2. Aims: The present study provides new and important information regarding skeletal metastases which may be more common with the introduction of laparoscopic cholecystectomy and should be excluded before radical resection is contemplated. 1.3. Settings and Design: This study was carried from 2010 to 2014. The study was approved by the review board and ethical committee of Institute of Medical Sciences, Banaras Hindu University Varanasi. 1.4. Methods and Material: After systemic examination, 95 patients of histopathologically proven and ultrasonographically diagnosed cases of carcinoma gallbladder (GBC) were subjected to contrast enhanced volumetric CT examination of abdomen and pelvis. 1.5. Statistical Analysis Used: Data were analyzed using the Statistical Package for Social Sciences (SPSS 16, Chicago, IL, USA). 1.6. Results: Four cases were found metastasizing to bones. In case of lumbar vertebral and iliac wing involvement the lesions were hyperdense suggesting osteoblastic metastasis. Osteolytic lesion was noted involving dorsal vertebra. Ala of sacrum showed mixed type of metastasis. All cases were seen in advanced stage of carcinoma. 1.7. Conclusion: To our knowledge, till date no longitudinal study has been done to assess incidence, type (osteolytic or osteoblastic or mixed), predisposing site and time of presentation (stage) of skeletal metastasis in GBC. The present study provides new and important information regarding the aggressive behaviour of GBC from an endemic geographical zone.
Authors and Affiliations
Amit Nandan Dhar Dwivedi
Keywords
Related Articles
- EP ID EP565458
- DOI 10.23880/crij-16000126
- Views 72
- Downloads 0
Invasive Glomus Jugulare Tumor (Type D2) in a Male - A Rare Case Report
1.1. Study Design A rare case report in a male and review of literature. 1.2. Objectives To describe a case report of invasive glomus jugulare tumor with intracranial extension. 1.3. Methods A 35 year old male complain...
Normal Esophagus Misdiagnosed as a Thyroid Nodule by Non-Radiologist Reading Thyroid US: Case Report
Ultrasound (US) of the thyroid gland represents one of the first diagnostic approaches in the characterization of thyroid nodules. Specific US features allow the radiologist to differentiate malignant versus benign patho...
Three-Dimensional Computed Tomographic Angiography (3DCTA) for the Diagnosis and Endovascular Treatment of a Ruptured Intercostal Artery Aneurysm Complicated By Neurofibromatosis Type 1
A 52-year-old man with neurofibromatosis type 1 (NF1) presented with sudden dyspnea and chest pain because of a spontaneous massive hemothorax. Three-dimensional computed tomographic angiography (3DCTA) revealed an inter...
An In-Vitro Cone-Beam Computed Tomographic Evaluation of Root Canal Anatomy of Permanent Mandibular Incisor Teeth in an Indian Population
The current study aimed to investigate the root canal anatomy and possible variations in permanent mandibular incisor teeth (central and lateral) of an Indian subpopulation, using three-dimensional cone-beam computed tom...
Pulmonary Infarction in Pulmonary Embolism
We present a case of 45-year-old woman who developed pulmonary infarction in pulmonary embolism, in a postoperative context. We review all imaging characteristics of this pathology, whose recognition is sometimes difficu...