Bony Secondaries and Dissemination in Advance Carcinoma Gallbladder: A Longitudinal Study
Journal Title: Clinical Radiology & Imaging Journal - Year 2018, Vol 2, Issue 3
Abstract
1.1. Context: Metastasis in carcinoma gall bladder is uncommon and occurs late in the course of the disease. Of all the distant sites that can be involved, the skeletal system is the least common site. We hereby present a prospective longitudinal study depicting the incidence, type, predisposing site and time of presentation of skeletal metastasis in carcinoma gallbladder. 1.2. Aims: The present study provides new and important information regarding skeletal metastases which may be more common with the introduction of laparoscopic cholecystectomy and should be excluded before radical resection is contemplated. 1.3. Settings and Design: This study was carried from 2010 to 2014. The study was approved by the review board and ethical committee of Institute of Medical Sciences, Banaras Hindu University Varanasi. 1.4. Methods and Material: After systemic examination, 95 patients of histopathologically proven and ultrasonographically diagnosed cases of carcinoma gallbladder (GBC) were subjected to contrast enhanced volumetric CT examination of abdomen and pelvis. 1.5. Statistical Analysis Used: Data were analyzed using the Statistical Package for Social Sciences (SPSS 16, Chicago, IL, USA). 1.6. Results: Four cases were found metastasizing to bones. In case of lumbar vertebral and iliac wing involvement the lesions were hyperdense suggesting osteoblastic metastasis. Osteolytic lesion was noted involving dorsal vertebra. Ala of sacrum showed mixed type of metastasis. All cases were seen in advanced stage of carcinoma. 1.7. Conclusion: To our knowledge, till date no longitudinal study has been done to assess incidence, type (osteolytic or osteoblastic or mixed), predisposing site and time of presentation (stage) of skeletal metastasis in GBC. The present study provides new and important information regarding the aggressive behaviour of GBC from an endemic geographical zone.
Authors and Affiliations
Amit Nandan Dhar Dwivedi
Keywords
Related Articles
- EP ID EP565458
- DOI 10.23880/crij-16000126
- Views 79
- Downloads 0
The New Classes of Synthetic Illicit Drugs Can Significantly Harm the Brain: A Neuro Imaging Perspective with Full Review of MRI Findings
Synthetic drugs contain substances that are pharmacologically similar to those found in traditional illicit drugs. Some of the most commonly abused synthetic drugs include synthetic marijuana, bath salts, ecstasy, N-bomb...
IgG4-Related Disease Mimicking Cholangiocarcinoma
Immunoglobulin G4-related disease (IgG4-RD) is an immune-mediated fibro-inflammatory disease that consists of a collection of disorders that share particular pathologic, serologic, and clinical features [1,2]. These diso...
Imaging of Langerhans Cell Histocytosis in an Adult
Langerhans Cell Histocytosis (LCH) is a rare disease of clonal dendritic cells which may affect any organ of the body. The disease is more common in children aged 0-15 years. It is very rare in adults. The current knowle...
Evaluation of 3DCT & MPR in Diagnosis of Craniofacial Fractures in Sudanese Population
1.1. Aims To determine sensitivity of three-dimensional computed tomography and multiplanar reconstruction in imaging cranifacial fractures in khartoum state 2017. 1.2. Methodology Descriptive, analytical study, were d...
Advanced Imaging Tools in the Evaluation of Epileptogenic Foci in the Pediatric Population
Focal cortical dysplasia (FCD) is a known cause of intractable epilepsy in the pediatric population. It is caused by disorganization of cortical neurons, which results in an epileptogenic focus that may be isolated or as...