Brain and immune system: KURU disease a toxicological process?
Journal Title: Journal of Neuroscience and Neurological Disorders - Year 2018, Vol 2, Issue 1
Abstract
Starting from observation of pathogenesis of KURU disease we try to investigate the immunologic role played by central nervous systems. A deeply knowledge in the transmission model of this pathology can be an imaging/diagnostic tool to Verify the progression of this prion molecule from gastro intestinal systems to the brain. (After cannibalistic behavior). The prions can be considered a sort of trace ant in KURU to monitoring this process and immune- brain relationship. Interesting information can be obtained useful to produce new pharmacological strategies in some other degenerative brain disease involving innate immune system activation.
Authors and Affiliations
M Luisetto, B Nili-Ahmadabadi, GR Mashori, A Yesvi, RK Sahu, Nasser H, luca Cabianca, Khan FA
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