Brainstem Auditory Evoked Potential in Preterm Infants and its Relation with Gestational Age
Journal Title: Journal of Clinical and Diagnostic Research - Year 2018, Vol 12, Issue 5
Abstract
ABSTRACT Introduction: Preterm births are associated with different neuro developmental abnormalities. During the last trimester of pregnancy, a part of foetal brain development occurs. Some area of the brain does not show normal growth even after the birth of preterm babies. Due to advanced obstetric and neonatal care of the present time, neonatal complications and mortality has reduced substantially. However, the preterm newborns experience many perinatal developmental abnormalities including prematurity of auditory pathway. Among the paediatric population, subjective tests for auditory evaluation are non reliable. Brainstem Evoked Response Audiometry (BERA), which assesses Brainstem Auditory Evoked Potential (BAEP), is a simple, non-invasive and an objective way of evaluating functional integrity of auditory pathway. Aim: To assess the neurological maturation and integrity of the auditory pathway by BAEP in preterm infants with respect to the gestational age. Materials and Methods: The present cross-sectional study was done in the Eastern region of India. A total of 74 preterm infants and 30 fullterm infants were included from the Department of Paeadiatrics, R.G. Kar Medical College, Kolkata, India. In the Department of Physiology, BAEPs were compared among preterm and full-term infants. The preterm babies were divided into three subgroups according to gestational age, Group 1 (≤28 weeks); Group 2 (29-32 weeks); Group 3 (33-36 weeks). Intergroup comparison was done by Student’s t-test, ANOVA and Post-Hoc test. Results: Preterm babies had prolonged wave I, wave V latency and I-V Interwave latency in the right ear (p<0.05) In Group 1, wave V and I-V latency were prolonged in both the sides. Right sided prolongation of wave I and wave V latency were present in Group 2. Left I-V interwave latency was prolonged in Group 1 than Group 3. A total of 24 preterm infants had absent waves. Conclusion: Preterm infants had premature peripheral and central auditory pathway. Group 1 showed central pathway immaturity compared to term infants and Group 3. Group 2 showed immature peripheral pathway. Absent waves were present in all the groups but maximum in Group 3, suggestive of dysfunction of auditory pathway but exact location of pathology was uncertain.
Authors and Affiliations
Hiya Bhattacharya, Sonali Majumdar Das, Gobinda Chandra Das, Anilbaran Singhamahapatra
Keywords
Related Articles
- EP ID EP522335
- DOI 10.7860/JCDR/2018/34294.11548
- Views 63
- Downloads 0
Perception of School Teachers towards Inclusive Education System in Jodhpur City, Rajasthan, India
ABSTRACT Introduction: Many disabled children receive rehabilitation but they find it difficult to get school admission. For successful inclusion, teacher’s attitudes and their perception towards disabled children play a...
Aloe vera for Dry Mouth Denture Patients – Palliative Therapy
Introduction: Xerostomia (dry mouth) is dryness of the mouth which is due to reduced salivary flow. Lack of adequate saliva causes discomfort in denture wearing patients and decreases retention of dentures. The ability o...
Pattern of Self Prescribed Analgesic Use in a Rural Area of Delhi: Exploring the Potential Role of Internet
Introduction: Analgesics are the most common self prescribed drugs. Although considered to be relatively safe, side effects are often seen when these drugs are used for prolonged period, in high doses or used where contr...
A Retrospective Study of Paediatric Dengue Cases in a Tertiary Care Hospital in Southern India
Introduction: Dengue is an important arthropod-borne viral infection in humans and is the second most important re-emerging tropical disease. Children are particularly at risk of developing severe dengue and clinically i...
Comparison of Central Corneal Thickness using Anterior Segment Optical Coherence Tomography Versus Ultrasound Pachymetry
Introduction: Corneal thickness is an important and sensitive indicator of corneal health. It is useful in monitoring corneal diseases such as corneal oedema and keratoconus, and selecting patients for refractive surgery...