Breast Conservation Surgery after Neoadjuvant Chemotherapy in Responders in Operable Breast Carcinoma: A Better Alternative
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 5
Abstract
Background: This was follow up of twenty five female patients of operable breast cancer in a prospective study in a tertiary care centre over a period of one year from 1st September,2006 to 31st August,2007 regarding response to neoadjuvant chemotherapy and conversion of modified radical mastectomy to breast conservation surgery. Aim: To observe the events during years of follow up and to study whether breast conservation surgery in carefully selected responders could prove to be a better alternative. Material and Methods: The study was conducted in fine needle aspiration cytology proven operable breast cancer patients with ductal histology. Inclusion criteria were female patients with complete haemogram, liver function tests, renal function tests within normal limits, Karnofsky score more than fifty and age below 70 years. Exclusion criteria were patients with pregnancy or previous history of thoracic irradiation. Results: 16 of 25 patients were offered breast conservation surgery after neoadjuvant chemotherapy according to selection criteria and kept on follow up after treatment completion. Two patients developed ipsilateral breast recurrence at four and six years of follow up respectively. Conclusion: Breast conservation surgery seems to be a safe and better alternative in carefully selected responders.
Authors and Affiliations
Kunjan Sharma
Keywords
Related Articles
- EP ID EP285403
- DOI -
- Views 70
- Downloads 0
Usefulness of routine haematological tests in neonatal septicaemia
Background: Neonatal septicaemia refers to a generalized bacterial infection in the first four weeks of life. It can be divided into two types: Early onset neonatal septicaemia (EONS) and Late onset neonatal septicaemia...
The Pattern of Microbial Keratitis in soft Contact Lens Wearers in a Tertiary Care Hospital in Eastern India
Background: Soft contact lenses are increasing in trend since a decade and are being used for both cosmetic and therapeutic purposes. Lack of compliance and poor hygiene towards lens care is one of the main causes associ...
Bacteriological Profile of Semen Specimens in Infertile Males
Introduction: Infertility constitutes a grave emotional and social problem in India. Male urogenital tract infection is one of the most important causes of male infertility and has been associated with 8-35% of male infe...
Clinical and Immunological Profile of Patients on Antiretroviral Therapy
Availability of antiretroviral therapy has changed the scenario of HIV endemic and now HIV disease has become a chronic manageable condition. Under NACP III nationwide free ART program was started. The purpose of this st...
Persistant Mullerian Duct Syndrome with Transverse Testicular Ectopia Presenting as Left Inguinal Hernia with Cryptorchidism, A Rare Presentation
Inguinal hernia and undescended testes in a patient can present with transverse testicular ectopia (TTE) and very rarely, with residual Mullerian duct structures. This is called persistent Mullerian duct syndrome (PMDS)....