Brig SPS Kochar’s Neovaginoplasty: Simple Technique
Journal Title: Journal of Medical Science And clinical Research - Year 2014, Vol 2, Issue 5
Abstract
Congenital anomaly in neonate is an alarming condition for parent as well as clinician. MayerRokitansky-Kuster-Hauser (MRKH) syndrome a rare congenital malformation of the female genital tract, has an incidence of 1 in 4,000 newborn girls (1). The syndrome, caused by an embryologic failure of the Mullerian ducts, is characterized by complete or partial agenesis of the vagina and uterus and can be associated with urinary tract, skeletal, and other congenital abnormalities (2).Individuals with MRKH syndrome commonly present with a nor-mal female 46,XX karyotype and regular ovarian endocrine function, leading to the good development of secondary sexual characteristics and normal adolescent progress in girls . The etiology of the syndrome, which is the second most common cause of primary amenorrhea, is yet unknown ( 3). The aetiology may be due to multifactorial mode of inheritance, which including genetic and environmental factors, probably is the most likely explanation (4 ) . MRKH syndrome along with complete androgen insensitivity syndrome are the most common causes of vaginal agenesis.
Authors and Affiliations
Gp Capt JC Sharma
Keywords
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