BRONCHODILATOR REVERSIBILITY IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Journal Title: PARIPEX-Indian Journal of Research - Year 2018, Vol 7, Issue 4
Abstract
Background:Although airflow obstruction in COPD is not fully reversible, patients can still exhibit clinically significant bronchodilator reversibility. This study assessed bronchodilator reversibility in COPD Materials and methods: Spirometric parameters were measured before and after inhaled 400 μg salbutamol. Responses were classified using the American Thoracic Society (ATS)/European Respiratory Society (ERS) criteria and patients were classified as reversible and irreversible. Result: There was a clear positive correlation between FEV reversibility and FVC reversibility. FEV increased significantly with 1 1 bronchodilator in 25% of COPD patients, a response that was normally distributed. FVC reversibility was seen in 62.5% of COPD Conclusion: COPD patients on the mild side of the severity spectrum differ from patients on the severe side regarding the association between their bronchodilator flow and volume responses.
Authors and Affiliations
Dr. Ajithkumar. C. S.
Keywords
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