Burkholderia Infections in Diabetic Patients Emerging as a Challenge for Physicians: A Case Series
Journal Title: Journal of Clinical and Diagnostic Research - Year 2019, Vol 13, Issue 3
Abstract
A BSTRACT The genus Burkholderia comprises more than 40 species. Medically important members of this genus are Burkholderia cepacia (B.cepacia), Burkholderia pseudomallei (B.pseudomallei) and Burkholderia mallei (B.mallei). Burkholderia cepacia complex (Bcc) can cause Cepacia syndrome which includes necrotising pneumonia, respiratory failure and bacteremia in Cystic Fibrosis (CF) patients and can be fatal. B.cepacia can be potentially pathogenic in individuals with impaired host defences and can cause pneumonia, bronchiectasis, pyopneumothorax and cavitatory lesions. The clinical manifestations of Melioidosis range from localised infection to overwhelming sepsis and death with Pneumonia being the most common presentation. The most significant risk factor for Melioidosis is diabetes. Musculoskeletal Melioidosis is not common in India even though sporadic cases have been reported mostly involving soft tissues. In the present two cases of Melioidosis in diabetics who presented with septic arthritis treated with surgical debridement followed by antibiotics and two cases of Cepacia syndrome in diabetics whose hospital course was complicated by pneumothorax and Acute Respiratory Distress Syndrome (ARDS). These reports raise the concern regarding the potential severity of Burkholderia infections and prompts early diagnosis by physicians to prevent morbidity and mortality.
Authors and Affiliations
Shubhransu Patro, Sudhansu Sekhar Panda, Debashish Mishra, Sonapuram Keerthi
Keywords
Related Articles
- EP ID EP581862
- DOI 10.7860/JCDR/2019/39889.12671
- Views 82
- Downloads 0
Sodium Valproate Induced Alopecia: A Case Series
Drug induced alopecia may range from a barely detectable shedding to an irreversible baldness. Alopecia associated with valproate is a dose-dependent and reversible side effect. We hereby report, three cases of alopecia...
MR Imaging of Rotator Cuff Tears: Correlation with Arthroscopy
Introduction: Rotator cuff tears are quite common and can cause significant disability. Magnetic Resonance Imaging (MRI) has now emerged as the modality of choice in the preoperative evaluation of patients with rotator c...
The Reliability of Panoramic Radiographs in the Evaluation of Location for Impacted Maxillary Canine Teeth: Comparison of Prediction Methods
ABSTRACT Introduction: The sagittal locations of Impacted Maxillary Canine (IMC) can be predicted on panoramic radiographs (OPGs). In general, the prediction methods that include the superimposition of the IMC crown on t...
Photographic Assessment of Cephalometric Measurements in Skeletal Class II Cases: A Comparative Study
Introduction: Cephalometry has many limitations of which radiation exposure is most important. Hence, there is a need to resort to other safer methods which could give equal if not better results. Aim: The purpose of thi...
Corneal Collagen Cross-linking for Treatment of Bacterial and Herpetic Keratitis
Introduction: Optimal management of infective keratitis is a formidable challenge and subject of ongoing studies. Recently, Collagen Cross-Linking (CXL) of the cornea has been considered to be a new effective therapeutic...