C-REACTIVE PROTEIN – A MARKER TO PREDICT THE OUTCOME OF PATIENTS WITH ACUTE ISCHEMIC STROKE
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2019, Vol 6, Issue 6
Abstract
BACKGROUND C-reactive protein is an inflammatory marker. The inflammation plays an important role in the atherogenesis. There is an evidence of the prognostic importance of C-reactive protein (CRP) in ischemic stroke. In this study, we assessed the prognostic values of CRP in ischemic stroke and predicting outcomes. Aims and Objectives- To evaluate the role of CRP in acute ischemic stroke. To assess the levels of CRP in acute ischemic stroke and in follow-up and CRP as a risk factor in acute ischemic stroke MATERIALS AND METHODS We studied 71 patients admitted in department of general medicine, Karnataka Institute of Medical Sciences (KIMS), Hubli, with either hypertension or diabetes or both or none without thrombolysis. Patients with first ever acute ischemic stroke, were examined considering all inclusion and exclusion criteria. CT scan of brain is done in all patients to confirm ischemic stroke and plasma CRP level was measured in all CT confirmed patients, and patients were followed-up for a period of three months and reassessed by NIHS scale and plasma CRP level. RESULTS In the ischemic stroke, we found that serum CRP level on admission was predictive of stroke severity (positively correlated with NIHSS), CRP was elevated >6 mg/dl in 50 patients out of 71 patients at the time of admission which was statistically significant. High CRP was associated with high NIHSS and high long-term mortality. CONCLUSION The CRP level is significantly higher in ischemic stroke and its elevation between 12-72 hours of symptom onset is a bad prognostic indicator. Elevated CRP level was a risk factor in association with other risk factors like diabetes hypertension.
Authors and Affiliations
Sanjay Neeralagi, Chandrashekar K, Ajmeer Pasha, Chetan K. Ganteppanavar, Praveen N
Keywords
Related Articles
- EP ID EP610157
- DOI 10.18410/jebmh/2019/74
- Views 82
- Downloads 0
ORBITAL CYSTICERCOSIS MASQUERADING AS INTERNUCLEAR OPHTHALMOPLEGIA
A Muslim lady, 24 year old presented with complaints of headache, orbital pain and right eye adduction deficit mimicking Internuclear Ophthalmoplegia. However absence of diplopia in primary or left gaze made us look for...
OCULAR ASPECTS OF HYPERTHYROIDISM WITH SPECIAL REFERENCE TO OCULAR MYOPATHY
BACKGROUND Hyperthyroidism can result in ocular manifestations even before systemic signs and symptoms develop. It is seen more in females and severe forms are more common in males. Early detection of ocular involvement...
EVALUATION OF VARIATIONS OF PORTAL VEIN BRANCHING BY MULTIDETECTOR COMPUTED TOMOGRAPHY
BACKGROUND Variations of the main portal vein (MPV) and right portal vein (RPV) branching at the hepatic hilum are quite frequent. Identification and reporting of such variations are necessary prior to interventions such...
A THREE YEAR STUDY OF SKIN CANCER IN A CASE WITH XERODERMA PIGMENTOSUM
Xeroderma pigmentosa was first described by Hebra and Kaposis. [1] It’s a rare disorder transmitted by autosomal recessive manner. [2,3] Xeroderma characterized by dry, pigmented skin lesions resultant of severe sensitiv...
HYPOMAGNESAEMIA IN PROTEIN ENERGY MALNUTRITION
INTRODUCTION: Protein energy malnutrition is one of the leading causes of childhood mortality and morbidity in developing countries. (1) It is a global health problem which starts in womb and ends in tomb. Protein energy...