C-reactive Protein as a Morbidity Predictor in Ischemic Stroke
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2018, Vol 5, Issue 11
Abstract
Introduction: Cerebrovascular accident (CVA) is an important health problem worldwide. Various studies proved that C-reactive protein (CRP) at admission was found to be a predictor of functional disability in ischemic CVA. Inflammation also regulates the production of the acute phase proteins such as CRP, fibrinogen, and serum amyloid A. CRP is one of the substances, present in the atherosclerotic lesion, more specifically in the vascular intima. Aim: The aim of the study was to evaluate the role of CRP as a morbidity predictor in acute ischemic stroke, to study the CRP level pattern in ischemic stroke and to study the correlation between severity level of stroke and CRP level. Materials and Methods: The study of CRP in ischemic stroke was carried out in the medical wards of Department of Medicine, Tirunelveli Medical College. We examined the association between the level of CRP at different stages after stroke and outcome. Results: Among patient with positive CRP, 13 were male and eight were female CRP level status positive in 21 patients. There is no association between age of patient and CRP and age factor does not influence the group pattern. Severe disability is more in CRP positive compared to CRP negative group. Conclusion: CRP is increased in a significant fraction of ischemic stroke. Patients with increased CRP had invariably more deficit during admission and patients with low CRP had good prognostic outcome 4 weeks after onset of stroke.
Authors and Affiliations
C Ilango, G Rathnakumar, Heber Anandan
Keywords
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