C-REACTIVE PROTEIN IN PREMATURE RUPTURE OF MEMBRANE WITH RESPECT TO FETOMATERNAL OUTCOME
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2017, Vol 4, Issue 58
Abstract
BACKGROUND The incidence of PROM is about 10% of all pregnancies and 70% of them occur at term. Most of the Indian studies document an incidence of 7-12% for PROM of which 60-70% occurs at term. Rest of the 30-40% is contributed at preterm. The aim of the study is to study the usefulness of maternal CRP measurements in diagnosis of chorioamnionitis, puerperal endometritis, neonatal infectious morbidities and mortalities among patients with PROM ( both term and preterm). MATERIALS AND METHODS This is a hospital-based cross-sectional observational study where 100 premature rupture of membrane cases were diagnosed and observed for fetomaternal outcome by doing routine clinical, biochemical and serum CRP examinations. RESULTS Maximum number of chorioamnionitis (16%) has developed when duration of rupture was for more than 36 hrs. PROM patients with latent period of ≥36 hrs had poorer neonatal outcome; i.e. 54.83% neonatal morbidity and 84.61% neonatal mortality were seen when duration of rupture was more than 36 hrs. 47.36% of CRP positive PROM women had developed chorioamnionitis during the course of delivery or postpartum. 49.12% of CRP positive PROM women had developed preterm delivery. CRP positive PROM women had poorer neonatal outcome; i.e. 82.35% neonatal morbidity and mortality has noted in babies delivered from CRP positive mother. CONCLUSION Careful antenatal monitoring, detection and prompt treatment of infection is necessary. Strict aseptic precautions, appropriate therapy, regular antenatal follow up are important features in the prevention and management of PROM. Evaluation of CRP in blood has helped to predict development of chorioamnionitis and preterm delivery following PROM and also perinatal morbidity and mortality.
Authors and Affiliations
Ojaswini Patel, Sharmila Pradhan, Mihir Meher, Bulu Naik
TOOL FOR EDUCATIONAL PROGRESS IT IS AN ART IN THE SETTING OF A GOOD QUESTION PAPER FOR EXAMINATION APPEARING STUDENTS
BACKGROUND Examination has always been an important part of the total educational process. Examinations are designed and administered at different stages of education and their results are used for various purposes like...
MANAGEMENT OF APPENDICULAR LUMP AT TERTIARY CARE HOSPITAL
BACKGROUND Among the acute surgical conditions, acute appendicitis is encountered in 2-6% of Patients. If appendectomy is not done, a lump is formed in about 3-6% of cases. After the onset of symptoms, a lump is formed a...
CT MEASUREMENTS OF TWO CEREBROVENTRICULAR INDICES AND THEIR RELATION WITH AGE
BACKGROUND Cerebroventricular Indices are the relative measurements of the size of lateral ventricle to that of brain. A normal study of these indices are necessary in order to understand any changes in size of the ventr...
AN ASSESSMENT OF AWARENESS ABOUT ORGAN DONATION AMONG PUBLIC
: Although organ transplantation can save many lives, there is a shortage of organ donors. One of the reasons for shortage of donors may be unawareness about organ donation. We conducted a cross-sectional study to assess...
STUDY OF OPEN CARPAL TUNNEL DECOMPRESSION UNDER LOCAL ANAESTHESIA WITHOUT TOURNIQUET
BACKGROUND Carpal tunnel syndrome is the entrapment neuropathy of the median nerve. It is more common in females than males, surgery is indicated when conservative treatment fails. AIM OF THE STUDY To assess the effectiv...