CA-19-9 as an Emerging Marker of Ovarian Tumour: A Rare Entity
Journal Title: Journal of Clinical and Diagnostic Research - Year 2019, Vol 13, Issue 5
Abstract
ABSTRACT Tumour markers are widely used in clinical practice for diagnosis; follow-up, prognosis and to predict recurrence of certain malignancies. Markers for ovarian cancer include CA-125 antigen, CA-15-3 antigen, and Carcino-Embryonic Antigen (CEA). CA-19-9 antigen is usually elevated in malignancies including colorectal carcinoma, pancreatic adenocarcinoma but significantly raised levels of <10,000 U/mL were seen in advanced stage of gastrointestinal malignancy. A reported case of 60-year-old female who had abnormally high levels of CA19-9 in the blood associated with mucinous carcinoma right ovary invasive endocervical type. At one month post surgery CA 19-9 dropped significantly. There are few case reports which have shown an association of raised CA19-9 with benign pathology but the present case is first case showing such high levels of CA19-9 associated with mucinous carcinoma of ovary. This highlights the fact that although CA19-9 is a marker of gastrointestinal malignancy; thorough evaluation to rule out ovarian malignancy in suspected cases should be done.
Authors and Affiliations
Alpana Singh, Astha Srivastava, Divya Chauhan, Rajeshwari Gautam, Gita Radhakrishnan
Keywords
Related Articles
- EP ID EP583436
- DOI 10.7860/JCDR/2019/39751.12843
- Views 78
- Downloads 0
Rare Isolate of Stephanoascus ciferrii from the Aural Discharge of Post-mastoidectomy Patient-A Case Report
ABSTRACT Stephanoascus ciferrii is an ascomycetous yeast-like fungus, rarely causing human infections. It is also a teleomorph of Candida ciferrii. This species has a strong tendency to become resistant especially in pat...
A Rare Familial Presentation of Facial Talon Cusp
Talon cusp is a rare developmental anomaly presenting as a wisp like structure arising from the cervical region of anterior teeth. They are predominantly seen in permanent dentition with a male predilection and are commo...
The Bivariate Correlation of Health Literacy and Cell Phone Addiction amongst Iranian Healthcare Students
ABSTRACT Introduction: Health Literacy (HL) is negatively associated with substance addiction. However, no study has examined the bivariate correlation of HL with cell phone addiction. Aim: To investigate the correlation...
Isolation of Haemophilus influenzae from Urine of an Elderly Male Patient with Carcinoma Bladder-An Under-recognised Pathogen?
ABSTRACT Haemophilus species are rare uropathogens. The incidence and significance of Haemophilus species isolated from the genitourinary tract are not well studied. Here we describe the serendipitous isolation of Haemop...
A Five-year Retrospective Study on the Clinical Profile of Myasthenia Gravis with Ocular Involvement in a Tertiary Hospital
ABSTRACT Introduction: Myasthenia Gravis (MG) with ocular involvement has an elusive diagnosis. Ptosis and Diplopia are the most common and early presenting features of MG. Acetylcholine receptor (AChR) antibody titre, N...