Caffeine as a modifying agent in acrylic hydrogels

Journal Title: Engineering of Biomaterials / Inżynieria Biomateriałów - Year 2017, Vol 20, Issue 142

Abstract

Hydrogels are materials created by polymer chains, that form a three-dimensional and crosslinked structure. These polymers are characterized by a very high sorption capacity, therefore they belong to the group of substances known as superabsorbents. Due to their properties hydrogels are often used in tissue engineering, drug delivery systems and as components of modern wound dressings. The aim of the study is to evaluate the effect of introduction of caffeine into the polymer matrix on the properties and structure of hydrogels. The scope of work included the synthesis and modification of the polymer matrix as well as studies on such prepared materials. Research involved in vitro incubation, spectroscopic analysis, studies on degradation and characterization of other physico-chemical properties. In this article series of hydrogels based on acrylic acid and modified with different amount of caffeine have been synthesized. The sorption capacity of obtained hydrogels in the liquids with compositions similar to the human body fluids has been tested. The stability of synthesized materials in simulated body fluids such as Ringer’s solution and artificial saliva has also been analysed. Based on conducted research it can be said that prepared materials do not change pH value of a liquid in which they are immersed. What is more, they are able to release entrapped caffeine. On the basis of such results it can be concluded that proposed acrylic acid based materials obtained by means of photopolymerization can be used in such areas as medicine or cosmetology.

Authors and Affiliations

B. Tyliszczak, S. Kudłacik-Kramarczyk, A. Drabczyk

Keywords

Related Articles

Właściwości mechaniczne stabilizatorów zewnętrznych "Carboelastofix" z kompozytów polimerowowęglowych do zespalania kości

Zrost pourazowy kości zależy od wielu czynników. Jednym z najważniejszych jest uzyskanie izoelastycznego zespolenia, którego sztywność będzie zmniejszać się w miarę postępu gojenia, i które umożliwi niewielkie ruchy poos...

Comparative study of bioresorbable membranes „Collapan” and „Collost” for the prevention of lower jaw atrophy

Prevention of the alveolar bone atrophy represents one of the urgent problems in oral and maxillofacial surgery. The aim of the study was comparative evaluation of two osteoplastic bioresorbable membranes: “Collapan” mad...

Liposomes as carriers for the delivery of active substances to the skin

Since ancient times cosmetics and dermatological medicines have been applied to the skin. Presently growing interest in topical administration in order to achieve therapeutic or good cosmetic effects can be noticed. Effe...

Influence of environmental factors on contact lenses properties

Nowadays contact lenses are a very common way of vision correction. To be used successfully, they must meet a number of conditions. This article describes studies on the influence of environmental factors such as low tem...

Preparation of composite filaments and 3D prints based on PLA modified with carbon materials with the potential applications in tissue engineering

This paper discusses the possibilities of obtaining polylactide-based composites and nanocomposites modified with carbon materials using the extrusion method, as well as the potential of their application in 3D printing...

Download PDF file
  • EP ID EP483530
  • DOI -
  • Views 85
  • Downloads 0

How To Cite

B. Tyliszczak, S. Kudłacik-Kramarczyk, A. Drabczyk (2017). Caffeine as a modifying agent in acrylic hydrogels. Engineering of Biomaterials / Inżynieria Biomateriałów, 20(142), 17-24. https://europub.co.uk/articles/-A-483530