Can a urine test predict osteoporotic fracture?
Journal Title: International Journal of Orthopaedics Sciences - Year 2018, Vol 4, Issue 1
Abstract
Objective: The aim of this study is to find out whether urinary telopeptide measurement can diagnose osteoporosis. Materials and Method: The study was conducted among patients who come to Sri Ramachandra hospital as inpatient or out patient during the period October 2015 to October 2017. Institutional ethics committee approval was obtained prior to the study. The inclusion criteria for the study were women aged 65 or older, Women age > 60 with risk factors, Younger postmenopausal women with one or more risk factors, (other than being female), Men aged 70 or older
and Men > 50 with risk factors and any person having fresh fragility fracture. The patients with confirmed osteopenia/osteoporosis based on DEXA scan forms the case group and age and gender matched control without osteopenia/osteoporosis forms the control group. The results from DEXA scan were taken as gold standard against urinary n telopeptide. Results: Fifty persons had DEXA normal and became control while twenty osteopenic and forty osteoporotic persons formed the case group. We had 47 persons in cases group (Osteoporotic) having fractures and seven from control group having fracture. The mean value of urinary n telopeptide in cases and control were 182.5 and 49.8 respectively. Conclusion: Urinary n telopeptide is a dynamic measurement of what is actually happening in bone at any given time. Hence simple urine test - Urinary n telopeptide can be used to diagnose osteoporosis.
Authors and Affiliations
Dr. Ganesan G Ram, Dr. PV Vijayaraghavan
Keywords
Related Articles
- EP ID EP485938
- DOI 10.22271/ortho.2018.v4.i1p.152
- Views 90
- Downloads 0
Is trochanteric fixation nail a better implant in the management of intertrochanteric fracture in elderly compared to dynamic hip screw
Background: Intertrochanteric fractures are the most common fractures in elderly and have devastating sequence if not managed properly. The ultimate goal in the management of Intertrochanteric fracture is early mobilizat...
Assessment of radiological outcomes in gap non-union of long bones using non-vascularised fibular strut graft augmented with corticocancellous graft
Background: A prospective study was conducted in the department of Orthopaedics & Traumatology in Dr. D.Y Patil Hospital, Navi Mumbai from January 2015 to June 2017 to assess radiological outcomes in traumatic gap non-un...
Posterior only debridement and instrumentation in thoracolumbar spinal tuberculosis
Introduction: Spinal tuberculosis is the most common form of skeletal tuberculosis with the dorsolubar region being the most commonly affected region. The most dreaded complication of spinal tuberculosis is tubercular pa...
Avascular necrosis of the femoral head due to sickle-cell disease in tribal population around Vishakhapatnam district, treated with core de-compression and non - vascularised fibular graft
Sickle-cell disease (SCD) is the most common cause of avascular necrosis (AVN) of the hip in childhood. It results in significant physical impairment and chronic pain, and ohen progresses to require hip replacement. Cons...
A novel technique of plate positioning for fixation of posterior column acetabular fractures by modified Kocher-Langenbeck technique: A case series
Introduction: Modified kocher-langenbeck technique aims at achieving osteosynthesis by creating two windows: between the gluteus medius and piriformis superiorly and between external rotators and ischial tuberosity infer...