Candida Infection in Intensive Care Unit Patients at Tertiary Care Hospital
Journal Title: Healthline - Year 2015, Vol 6, Issue 1
Abstract
[b]Introduction:[/b]Candidiasis is an opportunistic infection, an important cause of morbidity and mortality among the critically illIntensive Care Unit (ICU)patients. [b]Objective :[/b] The main aim of this study is to examine the trend of Candida infection in Intensive Care Unit (ICU) patients and to compare it with co- morbidities. All the patients admitted to Intensive Care Unit (ICU)were included in this study. [b]Method :[/b] A clinical and laboratory study of critically ill patients admitted at adult ICU, Civil hospital, Ahmedabad from August-October 2014 was done. Laboratory findings of cultures including the infecting Candida species, resistance to antifungals and clinical profile along with associated risk factors were analyzed. Overall 45 patients with positive blood culture and 116 patients with positive urine culture were included in the study. [b]Results : [/b]Total 32 cases of candidiasis were identified over the study period which includes 4 cases of candidemia and 28 cases of candiduria. The most common co-morbidities were prolonged ICU stay [for more than 4 days (100%)], multiple antibiotics [more than two (100%)], urinary catheterization (100%), diabetes (25%), mechanical ventilator support (31.25%) and central venous catheterization (9.3%). C. kruseiwas the most common species identified in blood and C. tropicalis in urine. The rates of susceptibility to antifungal agents were found as Amphotericin B (100%), Voriconazole (97%), Fluconazole (81%), Itraconazole (75%) and Miconazole (47%).[b] Conclusions :[/b] Prevalence of candidiasis in ICU is significantly high than general wards (p<0.0001). Most patients had one or more co-morbidities at the time of the diagnosis of candidemia. Prolonged ICU stay, multiple antibiotics, prolonged indwelling devices and diabetes mellitus were the common underlying conditions documented prior to candidemia.
Authors and Affiliations
Nidhi Barot, Mahendra Vegad, Sumeeta Soni, Kamal Sharma, Komal Shah
Keywords
Related Articles
- EP ID EP106074
- DOI -
- Views 104
- Downloads 0
Knowledge about Eye Diseases and Eye Care Needs in School going Children among Teachers and Children of a City located in Western India
Background: Knowledge about eye diseases in school children is important as six percent to seven percent (6-7%) children aged 10-14 years have problems with their eyesight affecting their learning in...
Assessment of Judicious Use of Immunologicals in Post Exposure Prophylaxis of Animal Bite Cases by Medical Officers in Government Health Centers in an Urban Area of Southern Rajasthan
Rabies is a hundred percent fatal disease with no cure being found till date. Only prompt reporting by the patient and correct prophylactic measures applied by the treating doctor can save a precious life in time. In Ra...
Assessment of Infrastructure and Logistics at Various Facilities Providing Sterilization Services in Rajkot District
Introduction : The National Population Policy 2000 and the Reproductive and Child Health (RCH) Programme Phase II emphasize the importance of achieving population stabilization and attaining the goal of replacement-level...
Trend of MDA Coverage and Compliance in the Four Endemic Districts of Jharkhand: A Secondary Data Analysis
Background: Lymphatic filariasis is one of the world’s leading causes of long term disability. It is not fatal, but it causes debility and imposes social and economic burden to the affected individuals, their families an...
Dengue : An Emerging Public Health Challenge
Epidemiological transition of the world with a focus on developing countries have resulted in the dual burden of diseases whereby non-communicable diseases (NCDs) are increasing without any [1] significant reduction of c...