CANDIDA KRUSEI A PREDOMINANT ISOLATE IN NEONATAL SEPTECEMIA: A PROSPECTIVE STUDY IN TERTIARY CARE HOSPITAL OF KASHMIR VALLEY
Journal Title: INTERNATIONAL JOURNAL OF PURE MEDICAL RESEARCH - Year 2019, Vol 4, Issue 1
Abstract
Background: Fungal infections are the emerging threat to the neonates in the hospitals taking over to bacteria. Candida infections a r e m a j o r c a u s e o f m o r b i d i t y a n d m o r t a l i t y i n immunocompromised hosts such as neonates. Most neonatal fungal infections are due to Candida species. This study was done with objectives to identify the predominant organisms causing septicemia in neonates and their pattern in Kashmir Valley. Methods: A prospective study was conducted in the Department of Microbiology GMC Srinagar in Neonates in the age group ranging from one day to four weeks admitted in the associated hospitals of the institution and suspected blood borne infections have been studied in the laboratory and blood culture samples were incubated in BacTAlert 3D (Biomerieux, India®) machine-driven blood culture system test) Results: 1090 sample were collected from neonates admitted in the NICU. The isolation rate was 868 (79.6%) and among them positive cultures 570 (65.6%) were Candida Krusei. 101 (11.6%) candida albicans, 30 (3.4%) Acinetobacter baumani and other bacterial growth was seen in 167 (19.2%) Conclusions: There is emerging trend of multi-drug-resistant organisms isolation from septicemic neonates. Nonalbicans Candida particularly Candida krusei has emerged as an important cause of neonatal septicemia. Routine susceptibility testing of Candida isolates by DD method should be conrmed by BMD-MIC method
Authors and Affiliations
Rubina Hakak, Abdul Rouf, Shabana Maqbool, Syed Badakhshan
Keywords
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