Candida Species Isolated From Blood Culture in Neonatal Septicemia Patients Admitted at RIMS, Ranchi
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 1
Abstract
Introduction: Candida species are a common cause of neonatal nosocomial bloodstream infections in premature baby, low birth weight baby and baby on prolonged antibiotic therapy, and are a leading cause of infectious-related mortality in the neonatal intensive care unit (NICU). The clinical manifestations are respiratory distress, feeding intolerance, bradycardia and abdominal distension. Blood cultures are the gold standard for detecting candidemia. Blood culture sensitivity is likely worse in premature infants, where blood culture volumes are less than 1 ml. Aims and Objective: Identification and speciation of the various candida species isolate. Materials and Methods: 455 (four hundred fifty five) neonate blood sample are collected in microbiology department RIMS Ranchi, over a period of 12 month July16 to June17). About 1-3 ml of blood was collected from peripheral vein of the infants under aseptic precaution and inoculated and processed by automated BD BACTEC FX system blood culture bottle. Identification of Candida species was done by using germ tube test, growth on corn meal agar, sugar fermentation test and sugar assimilation test. Results: Out of the 455 blood samples, 65 showed growth of candida species (prevalence 14.3%) Among 65 candida species, NAC (nonalbicans candida) species were responsible for 83.1% (54) cases with C. tropicalis 55.5% (30), C. parapsilosis 12.3% (8), C. glabrata 10.8% (7) and C. krusei 7.6% (5) as the most predominant species, wheres as 16.9% (11) of cases were caused by C. albicans. Conclusion: Low birth weight, premature and baby on broad spectrum antibiotic therapy are at higher risk of developing candidemia. In this study, prevalence of nonalbicans candida species were more common than candida albicans and among them C. tropicalis was most common.
Authors and Affiliations
Manoj Kumar, Ravindra Kumar Barnawal, Amber Prasad, Ashok Kumar Sharma, Kumari Seema, Versha Priydarshini
Keywords
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- EP ID EP531335
- DOI 10.21276/ijmrp.2018.4.1.136
- Views 78
- Downloads 0
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