Carbapenem Utilization among Adults Inpatients in One Private Hospital in Surabaya
Journal Title: Indonesian Journal of Clinical Pharmacy - Year 2017, Vol 6, Issue 4
Abstract
Carbapenem resistance is one of the most frightening health problems globally. What determines the occurrence of carbapenem resistance phenomenon is the widely, repeated, irresponsible utilization of carbapenem over a long period of time. This research was aimed to provide an overview of the carbapenem utilization and its appropriateness compared with the guidelines. This research was a descriptive research that analyzed medical record data of adult patients who used carbapenem from January to September 2014 in one private hospital in Surabaya. The carbapenem utilization was defined in defined daily dose (DDD). Identifying the appropriateness of antibiotics’ type, dosage regimen, and duration of treatment were conducted by using the newest Infectious Disease Society of America (IDSA) guidelines as the main reference and Drug Infomation Handbook 22th edition (2014) as the secondary reference. Moreover, the appropriateness of type of antibiotics used for each patient was also analyzed by comparing the actual dosage used with the microbiology culture results. There were 255 adult patient’s medical records used in the present research. The total amount of carbapenem utilization during the observation period was 1462.25 DDD. The density of carbapenem utilization could be considered as low, i.e. almost 20% of total inpatients per day being prescribed with carbapenem (19.39 DDD/100 bed‑days). There were 72.95% and 59.52% carbapenem utilization which were defined appropriate based on the analysis using IDSA guidelines and bacteria culture results respectively. Considering the profile of antibiotics utilization in this hospital, the antibiotics prescribing pattern could be improved to a more responsible pattern. Further researches exploring the relationship between pathogen resistance and carbapenem consumption need to be conducted in relation to the consideration in making local hospital regulation regarding the use of antibiotics in the hospital settings.
Authors and Affiliations
Steven V. Halim, Rika Yulia, Eko Setiawan
Keywords
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- EP ID EP370130
- DOI 10.15416/ijcp.2017.6.4.267
- Views 98
- Downloads 0
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