Carbon Nanomaterials as a Potential Agents for Induction of Apoptosis In Cancerous Tissue
Journal Title: Advances in Clinical Toxicology - Year 2021, Vol 6, Issue 2
Abstract
Cancerous condition is the result of abnormal physiological and cellular mechanisms that develop in an individual. The cells prone to cancer exhibit complexed behavioral abnormalities and disobedience to the normal cellular signaling pathways. Benign and malignant cancers show different proliferative behavior depending on the type of cells, their location, and functions. The cancerous tissues have increased vascular supply and a lower ratio of the rate of conversion of oxy-hemoglobin to deoxy-hemoglobin. In tissues, like the dense radiographic breast, show some morphological changes in the cell organelles like nuclei. The carbon nanoparticles act as suitable agents for carrying antiviral drugs, antibiotics, anticancer drugs, agents for imaging, and thermal ablation. Further, considering the multifaceted features, carbon nanomaterials can be a potential agent to induce apoptosis in the cancerous tissue that might help to restrict its growth. All these intentions need careful examinations, applications at laboratory, clinical, and mass-scale production, keeping in mind the environmental, judicial aspects, and human tendencies of maximizing their benefits. This short review is an effort to evaluate the potentials of carbon nanomaterials that can induce apoptosis in cancer tissue.
Authors and Affiliations
YK Lahir
GABA in Hepatic Proliferation and Regeneration
Gamma-amino butyric acid (GABA) is a ubiquitous four-carbon, non-protein amino with diverse physiological actions in various types of cells throughout the body. Studies, including ours, show that type A GABA receptor (G...
Stable Carbon and Nitrogen Isotopes of A Sentinel Species, the Western Alaska Red Fox (Vulpes Vulpes)
Mercury (Hg) is a metal of both natural and anthropogenic origins that bioaccumulates in wildlife. Environmental risk assessments to arctic wildlife, such as the red fox (Vulpes vulpes), often use mercury analysis of ha...
Unveiling of Potential Zika Virus RNA polymerase Inhibitors Using Structure based Virtual Screening
Zika virus (ZIKV) infection has been associated with Guillain-Barre syndrome in adults and Microcephaly in infants. However, there is no currently approved antiviral drug against ZIKV. The 103-kDa NS5 protein is the lar...
The Pathogenesis of Xenobiotic-Induced Oxidative Stress in the Cardiac Microenvironment
The heart functions to ensure optimal perfusion of every organ while maintaining elasticity and compliance. Mainly composed of cardiac myocytes, fibroblasts, endothelial and vascular cells, the heart has the highest ene...
Methyl Mercury, Adipokines, 3T3-L1 Cells and Diabetes
Diabetes is a contributor to morbidity across the globe and is often associated with obesity and metabolic syndrome. In addition to genetic and lifestyle factors, environmental factors such as metals and persistent orga...