Carboplatin and Paclitaxel as Induction Chemotherapy in Locally Advanced Head and Neck Cancer Patients
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 2
Abstract
Head and neck malignancies constitute about 3% of all newly diagnosed cancers in humans. Overall, 57.7% of global head and neck cancers occur in Asia, especially in India, for both sexes. Previously standard approach for locally advanced head and neck cancers was surgery followed by external beam radiation therapy(EBRT). Other approach was CRT i.e. concomitant chemotherapy and radiotherapy but systemic relapse was seen more by this approach due to a lack of systemic control. For this reason nowadays incorporation of induction chemotherapy is done in treatment of locally advanced head and neck cancers. Our study is a retrospective study done in 250 patients with locally advanced head and neck cancers. These patients were given carboplatin and paclitaxel as induction chemotherapy and the response of the patients and adverse effects of the drugs were noted.
Authors and Affiliations
Ajit Kumar, Neha Kurmi Patel, Lalit Mohan Patel
Keywords
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- EP ID EP464278
- DOI 10.9790/0853-1802011721.
- Views 68
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