Cardiac Arrest After Status Epilepticus: Bupropion and Ecstasy Intoxication
Journal Title: Türk Yoğun Bakım Dergisi - Year 2018, Vol 16, Issue 1
Abstract
Bupropion is a monocyclic antidepressant that has been known to cause seizures in high therapeutic doses or acute high doses. Bupropion is a selective norepinephrine, dopamine and minimally serotonin reuptake inhibitor. Overdose of bupropion may lead to recurrent seizures, hypoxia and death. It is important to be aware in terms of bradycardia-asystole as a significant consequence of seizure and hypoxia. Patients using high dose of bupropion should be closely monitored in terms of cardiological and neurological. In this study, we presented a 19 year-old female patient who did not have previous history of epilepsy but who used oral bupropion to reduce nicotine addiction. A status epilepticus and cardiac arrest developed in a case receiving 1,8 g bupropion for suicide. 3.4-methylenedioxy-N-methylamphetamine (MDMA) and benzodiazepine were detected in urine sample. We did not find any cases in the literature related to MDMA and bupropion overdose. Therefore, we presented this rare case.
Authors and Affiliations
Zübeyde Tuba Duran, Pınar Karabacak, Kemal Yetiş Gülsoy, Hatice Akdu, Füsun Eroğlu
Keywords
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- EP ID EP382221
- DOI 10.4274/tybd.74946
- Views 126
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