Cardiooncological balance in a 75-year-old male with a hepatocellular carcinoma CS IV and a congestive heart failure NYHA III „de novo”
Journal Title: OncoReview - Year 2015, Vol 5, Issue 2
Abstract
The case reports about a 75-years-old man without a previous medical history, in whom a heart failure NYHA III de novo was diagnosed together with persistent atrial fibrillation and hepatocellular carcinoma in clinical stage IV. Based on echocardiography and computed tomography there were pulmonary hypertension in course of lymphangiosis carcinomatosa as well as diffuse metastases in the abdomen diagnosed. Before the treatment initiation the patient was classified 3 in WHO performance status. After an improvement in control of the rhythm frequency and the heart failure treatment stabilisation with a β-blocker, an ACE-inhibitor, spironolactone and furosemide, the patient’s performance status improved to WHO 2. He was further disqualified from surgical procedures due to the advanced clinical stage of the oncological disease. Considering high probability of further cardiotoxic influence of sorafenib on the heart failure despite its satisfactory control, the patient was assigned to palliative chemotherapy with FOLFOX. Parallel he was strictly followed up cardiologically in an outpatient clinic what certainly supported the oncological treatment. The patient survived 32 weeks from the first hospitalization and the progression free survival was 12 weeks from the chemotherapy initiation.
Authors and Affiliations
Maciej Żechowicz, Konrad Wroński, Monika Rucińska
Keywords
Related Articles
- EP ID EP67780
- DOI -
- Views 205
- Downloads 0
Long-term survivor of advanced synovial sarcoma - case report and literature review
Progress in metastatic renal cell carcinoma treatment is generally based on new registered drugs. This brings improvement of results but it also needs the choice of proper drug. The decision is especially important in in...
Mental disorders in cancer patients - clinical approach
Cancer patient is struggling not only with the primary disease, but also is exposed to emotional states that at unfavorable conditions and heavy burden can lead to depression, increased anxiety, and in consequence cause...
The New Classification of NET
There are three imporant directions in the field of GEP NET. The first one is the NET Registry which collects the data from different clinical centers, that can be compared, providing the konwledge of these tumors. The s...
Why does reimbursement of orphan drugs require a specific approach?
The greatest problem concerning the reimbursement of orphan products is their high price. In the case of orphan drugs, reimbursement and pricing decisions are highly interrelated. In decisions concerning reimbursement of...
Primary cutaneous B-cell lymphoma located on the face and hard palate
[b]Introduction[/b]: Primary cutaneous B-cell lymphomas represent primary cutaneous lymphomas. The World Health Organization-European Organization for Research and Treatment of Cancer defines primary cutaneous B-cell lim...