Cardiovascular effects of methylphenidate in children with attention deficit hyperactivity disorder (ADHD)
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 6
Abstract
The present study was conceived with the objective to examine the effects of methylphenidate on cardiovascular variables in children with Attention-deficit/hyperactivity disorder (ADHD). ECG indices plus systolic blood pressure (SBP), diastolic BP (DBP) and heart rate (HR) were assessed in 52 children with ADHD (dosage of 0.3- 1 mg/ kg body weight). Cardiovascular parameters were assessed at baseline and 12 weeks. Small but statistically significant changes in DBP and HR were observed at 12 weeks without clinically meaningful changes in ECG. Increase in heart rate and Blood pressure could be attributed to the increased sympathetic activity caused by methylphenidate
Authors and Affiliations
Dr Pramesh Dogra
Keywords
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