Cardiovascular Manifestations of Dengue Fever Two Case Report and Review article
Journal Title: Journal of the Indian Medical Association - Year 2018, Vol 116, Issue 7
Abstract
Dengue is one of the most important viral diseases affecting human beings. The majority of symptomatic infections result in a relatively benign disease course. However, a small proportion of patients develop severe clinical manifestations due to platelet and endothelial dysfunction, immunological derangement with increased capillary permeability causing bleeding, hypovolaemic shock and cardiovascular collapse. Evidence is increasing that dengue can also cause myocardial impairment, arrhythmias and, occasionally, fulminant myocarditis. Here we are reporting two cases of Dengue fever presenting with Bradyarrhythmias (Atrioventricular Block) and another with myocarditis and heart failure. No antiviral agent is available till now and treatment remains supportive with judicious fluid replacement for patients with severe disease. Understanding of cardiovascular hemodyanamics in Dengue is important in the management specially during life threatening situation. In this Review Article we will outline the current understanding of the cardiovascular manifestations of dengue fever from the availalble literatures and conclude with a discussion of the possible therapeutic implication.
Authors and Affiliations
Kanak Kumar Mitra, Lipika Adhikari, Jyotirmay Pal, Uday Sankar Das, Palash Mondal, Tapobrata De
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