Carotid artery intima-media thickness is a marker for coronary artery disease
Journal Title: Scientific Journal of Medical Science - Year 2003, Vol 2, Issue 8
Abstract
Although cardiac mortality has declined over the past four decades, coronary artery disease (CAD) remains the leading cause of mortality worldwide. Considering the importance of CAD and effectiveness of primary prevention interventions (as are statins), is present an increasing interest in how to identify individuals with increased risk of cardiovascular incidents before they occur. Ultrasonography in B-mod of carotid arteries nowadays increasingly is using as a noninvasive and sophisticated method for evaluating the atherosclerotic load in various clinical situations. The aim of this study was to analyze the relationship between intima-media thickness of the carotid artery with the presence and extent of coronary disease. 50 patients with positive stress echocardiography are referred for coronary angiography for coronary atherosclerosis assessment. All these patients, and to 50 healthy volunteers are evaluated by B-mode ultrasound of common carotid arteries for carotid intima-media thickness (CIMT) assessment. It was shown that patients with CAD have higher values of CIMT than healthy volunteers (0.96 mm ± 0.16 mm versus 0.64 mm ± 0.0.89 mm; T-test=16.053, p<0.0001). Values of CIMT were in direct correlation with severity and extent of coronary artery disease. Values of CIMT were greater in the subgroup with three vessel disease and in the subgroup of left main coronary artery disease than they were in the subgroup with single vessel coronary artery disease and in subgroup with two vessel coronary artery disease (1.08 mm ± 0.23 mm and 1.05 mm ± 0.16 mm versus 0.87 mm ± 0.125 mm and 0.93 mm ± 0.06 mm; coefficient of correlation was r=0. 473 and this was statistically significant p<0.01). In conclusion, CIMT can be used to predict the presence and extent of coronary atherosclerosis.
Authors and Affiliations
S. Abdushi*| Regional Hospital “Prim.Dr. Daut Mustafa” in Prizren, Republic of Kosovo., F. U. Kryeziu| Institute of Public Health Prizren Branch, Republic of Kosovo., F. Mazreku| Regional Hospital “Prim.Dr. Daut Mustafa” in Prizren, Republic of Kosovo.
Keywords
Related Articles
- EP ID EP1241
- DOI 10.14196/sjms.v2.i8.894
- Views 489
- Downloads 25
A critical review on the efficacy of integrated child development service scheme with concern to growth progressions in early childhood
A growing body of evidence suggests that supplementary feeding programs have a positive effect on reducing malnutrition prevalence in developing countries. In India, despite substantial funding of its early childhood dev...
The study of effect of aqueous Cucurbita pepo linn seed extract on serum prolactin level of lactating female albino rats
Prolactin participation has been established for a growing number of physiological actions of these, the best studied is the stimulation of mammary gland development and induction of milk synthesis at the end of pregnanc...
Ovarian hyperstimulation syndrome (OHSS) in spontaneous pregnancy
It has been known that most cases of ovarianhyperstimulation syndrome (OHSS) are almost exclusively associated withcontrolled ovarian stimulation with gonadotrophins or occasionally, clomiphenecitrate. However, OHSS is a...
Epidemiology of hirsutism in Qassim region, KSA
Hirsutism is acommon clinical condition that usually has a benign course. A geneticabnormality causing hirsutism is supported by the observation that differentmembers of the same family are often affected.The goal of thi...
Advances in biomaterials, new strategies, development and applications for biomedicine and engineering
One of the most exciting and rewarding research areas of materials science involves the applications to health care, especially to skeletal repair and reconstructive surgery. The potential benefits of these materials for...