CASE REPORT: A RARE PRESENTATION OF HEMOGLOBIN D TRAIT
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2013, Vol 2, Issue 49
Abstract
Hemoglobin D Punjab was first discovered in the early fifties in a mixed British and American family of Indian origin from the Los Angeles area; hence it is also sometimes called as “D Los Angeles”. Hemoglobin D is the 4th common hemoglobin variance. It developed as a response to the selective pressures of malaria in these regions. The substitution in Hb D is a glutamic acid to glutamine at the 121stamino acid of the beta -globin chain (121Glu Gln). Hb D has an S-like mobility on alkaline electrophoresis but co-migrates with HbA on acid pH. Osmotic fragility may be decreased. Blood films may show target cells. [1]
Authors and Affiliations
Mythri S, Chikkalingiah , Keshava
Keywords
Related Articles
- EP ID EP111959
- DOI 10.14260/jemds/1667
- Views 80
- Downloads 0
THE ROLE OF XANTHINOL NICOTINATE WITH HEPARIN AND DEXTRAN-40 IN POST TRAUMATIC ARTERIAL REPAIR CASES WHERE IMMEDIATE DISTAL PULSATION IS ABSENT: A PROSPECTIVE STUDY IN 150 CASES PRESENTING MORE THAN 10 HOURS POST INJURY
[b]OBJECTIVE:[/b] The therapeutic role of Xanthinol nicotinate along with Heparin and Dextran-40 was studied in the management of 150 patients in whom distal pulsations were not felt immediately post arterial repair...
PREGNANCY OUTCOME AFTER MITRAL VALVE REPLACEMENT: A CASE REPORT[b][/b]
Cardiac disorders in pregnancy poses special challenges to health care providers. Complications may arise at any stage due to increased hemodynamic load imposed by pregnancy or because of impaired cardiac perf...
GLAUCOMA IN PUNJAB- AN OBSERVATIONAL STUDY
BACKGROUND Glaucoma is the second leading cause of blindness in the adult population in India. The global prevalence of glaucoma for population aged 40 to 80 years is estimated to be 3.54% and the projected number of peo...
CLINICOPATHOLOGICAL EVALUATION OF BENIGN BREAST DISORDERS IN DIFFERENT AGE GROUPSA SINGLE CENTRE STUDY
BACKGROUND In the past few decades, breast health has been widely discussed owing to the increasing prevalence of breast cancer. This study evaluated patients presenting with breast-related complaints to study the clinic...
ROLE OF FINE NEEDLE ASPIRATION CYTOLOGY IN BREAST CANCER SCREENING
BACKGROUND A cross sectional study for screening of carcinoma breast was done on pregnant women attending gynaecology and surgery OPD at District Hospital Samba, Jammu. All women with sign and symptoms of breast disease...